(S)-2-苯基-1-丙醇合成路线 （共 88 条）
反应条件
1: With lithium aluminium tetrahydride in diethyl ether 2: With water in diethyl ether
参考文献
Santaniello, Enzo; Casati, Silvana; Ciuffreda, Pierangela; Meroni, Giuseppe; Pedretti, Alessandro; Vistoli, Giulio
Tetrahedron Asymmetry, 2009 , vol. 20, # 16 p. 1833 - 1836
反应条件
N,N'-dimethyl-N,N'-propyleneurea; anhydrous 4,4'-bipyridyl; bis(cyclopentadienyl)titanium dichloride; manganese; NiCl2*0.97C2H6O; triethyl amine hydrochloride T=20°C; 12 h; Inert atmosphereGlovebox;
参考文献
Zhao, Yang; Weix, Daniel J.
Journal of the American Chemical Society, 2014 , vol. 136, # 1 p. 48 - 51
反应条件
1: InI3 / dichloromethane / 0.05 h / 20 °C 2: InI3; phenyl silane / dichloromethane / 1 h / 20 °C View Scheme
参考文献
Inamoto, Yoshihiro; Nishimoto, Yoshihiro; Yasuda, Makoto; Baba, Akio
Chemistry Letters, 2013 , vol. 42, # 12 p. 1551 - 1553
反应条件
boron trifluoride diethyl etherate 144 h; Heating / reflux; Product distribution / selectivity;
参考文献
MONASH UNIVERSITY
Patent: WO2005/70911 A1, 2005 ;
Location in patent: Page/Page column 94 ;
反应条件
potassium hydroxide; porcine pancreatic lipase 1) porcine pancreatic lipase (PPL), 1-butanol, hexane,water, 30 deg C 2) CH3OH, 3 h, r.t.; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Chen, Ching-Shih; Liu, Yeuk-Chuen
Journal of Organic Chemistry, 1991 , vol. 56, # 5 p. 1966 - 1968
反应条件
in hexane 2 h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Fukumasa; Furuhashi; Umezawa; Takahashi; Hirai
Tetrahedron Letters, 1991 , vol. 32, # 8 p. 1059 - 1062
反应条件
Lipase PS in tetrahydrofuran T=-20°C; Product distributionThermodynamic data; Further Variations:ReagentsTemperaturesReaction partnersSolvents;
参考文献
Cainelli, Gianfranco; Galletti, Paola; Giacomini, Daria; Gualandi, Andrea; Quintavalla, Arianna
Helvetica Chimica Acta, 2003 , vol. 86, # 11 p. 3548 - 3559
反应条件
Reaktion eines partiell racemischen Praeparats (<=a>D: -21grad <Bzl.>); Product distribution;
参考文献
Eliel; Freeman
Journal of the American Chemical Society, 1952 , vol. 74, p. 923,925
反应条件
potassium permanganate; sulfuric acid in acetone T=0 - 20°C; 4.5 h;
参考文献
Galletti, Paola; Pori, Matteo; Giacomini, Daria
Synlett, 2010 , # 17 p. 2644 - 2648
反应条件
2,2,6,6-tetramethyl-piperidine-N-oxyl; sodium hypochlorite; sodium chlorite in water; acetonitrile T=35°C; 4 h; aq. phosphate buffer;
参考文献
Galletti, Paola; Pori, Matteo; Giacomini, Daria
Synlett, 2010 , # 17 p. 2644 - 2648
