Boc-D-脯氨酸合成路线

参考文献

Costa, Brian R. de; Dominguez, Celia; He, Xiao-shu; Williams, Wanda; Radesca, Lilian; Bowen, Wayne
Journal of Medicinal Chemistry, 1992 , vol. 35, # 23 p. 4334 - 4343

186581-53-3重氮甲烷+

37784-17-1Boc-D-脯氨酸

152665-79-7(R)-2-(2-二氮杂乙酰基)吡咯烷-1-羧酸叔丁酯

参考文献

Abele, Stefan; Voegtli, Kurt; Seebach, Dieter
Helvetica Chimica Acta, 1999 , vol. 82, # 10 p. 1539 - 1558

37784-17-1Boc-D-脯氨酸

152665-79-7(R)-2-(2-二氮杂乙酰基)吡咯烷-1-羧酸叔丁酯

参考文献

Schjoth-Eskesen, Christina; Jensen, Henrik Helligso
Synthetic Communications, 2009 , vol. 39, # 18 p. 3243 - 3253

37784-17-1Boc-D-脯氨酸

201039-13-6(R)-2-(氰基甲基)吡咯烷-1-甲酸叔丁酯

参考文献

Journal of Medicinal Chemistry, , vol. 45, # 12 p. 2571 - 2578

37784-17-1Boc-D-脯氨酸

228244-20-0(R)-(+)-1-Boc-2-吡咯烷甲腈

参考文献

University of Virginia Patent Foundation
Patent: US2012/214858 A1, 2012 ;
Location in patent: Page/Page column 30 ;
US 20120214858 A1

37784-17-1Boc-D-脯氨酸

228244-04-0(S)-1-N-Boc-2-吡咯烷甲腈

参考文献

Kennedy, Andrew J.; Mathews, Thomas P.; Kharel, Yugesh; Field, Saundra D.; Moyer, Morgan L.; East, James E.; Houck, Joseph D.; Lynch, Kevin R.; MacDonald, Timothy L.
Journal of Medicinal Chemistry, 2011 , vol. 54, # 10 p. 3524 - 3548

37784-17-1Boc-D-脯氨酸+

124-40-3二甲胺

124072-81-7

参考文献

Yea, Christopher M.; Allan, Christine E.; Ashworth, Doreen M.; Barnett, James; Baxter, Andy J.; Broadbridge, Janice D.; Franklin, Richard J.; Hampton, Sally L.; Hudson, Peter; Horton, John A.; Jenkins, Paul D.; Penson, Andy M.; Pitt, Gary R. W.; Riviere, Pierre; Robson, Peter A.; Rooker, David P.; Semple, Graeme; Sheppard, Andy; Haigh, Robert M.; Roe, Michael B.
Journal of Medicinal Chemistry, 2008 , vol. 51, # 24 p. 8124 - 8134

104-86-9对氯苄胺+

37784-17-1Boc-D-脯氨酸

1140495-84-6(R)-2-(4-氯苄基氨基甲酰)吡咯烷-1-羧酸叔丁酯

参考文献

Merritt, J. Robert; James, Ray; Paradkar, Vidyadhar M.; Zhang, Chongwu; Liu, Ruiyan; Liu, Jinqi; Jacob, Biji; Chiriac, Camelia; Ohlmeyer, Michael J.; Quadros, Elizabeth; Wines, Pamela; Postelnek, Jennifer; Hicks, Catherine M.; Chen, Weiqing; Kimble, Earl F.; O'Brien, Linda; White, Nicole; Desai, Hema; Appell, Kenneth C.; Webb, Maria L.
Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 18 p. 5477 - 5479

37784-17-1Boc-D-脯氨酸

783325-25-7(2R)-2-[(甲基氨基)甲基]-1-吡咯烷羧酸叔丁酯

参考文献

Vu, Chi B.; Pan, Deborah; Peng, Bo; Kumaravel, Gnanasambandam; Smits, Glenn; Jin, Xiaowei; Phadke, Deepali; Engber, Thomas; Huang, Carol; Reilly, Jennifer; Tam, Stacy; Grant, Donna; Hetu, Gregg; Petter, Russell C.
Journal of Medicinal Chemistry, 2005 , vol. 48, # 6 p. 2009 - 2018

37784-17-1Boc-D-脯氨酸

5654-87-5

参考文献

Lopez-Cobenas, Alberto; Cledera, Pilar; Sanchez, J. Domingo; Lopez-Alvarado, Pilar; Ramos, M. Teresa; Avendano, Carmen; Menendez, J. Carlos
Synthesis, 2005 , # 19 art. no. C06905SS, p. 3412 - 3422