oxygen; Mn(CH3COO)2*4H2O; [Co(O2CCH3)2]*4H2O; acetic anhydride; acetic acid; potassium bromide T=110°C; 4.5 h; ConcentrationReagent/catalystTimeTemperaturePressure;

1: (1S,2S)-1,2-diaminocyclohexane; copper(l) iodide; caesium carbonate / 1,4-dioxane / 16 h / |Reflux 2: 4,4,5,5-tetramethyl-[1,3,2]dioxaborolane; tri-cyclo-hexyl-phosphine; bis(1,5-cyclooctadiene)nickel (0) / toluene / 20 h / 80 °C / |Glovebox; |Inert atmosphere View Scheme

1: bromine / 210 °C / Irradiation 2: aqueous ethanol / Erhitzen des Reaktionsprodukts mit wss.-aethanol. Kalilauge View Scheme

lithium bromide; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride in tetrahydrofuran T=-20 - 80°C; Inert atmosphere;

bromine; iodine; iron in tetrachloromethane 4 h; Ambient temperature;

bromine T=210°C; Irradiation;

1: (i) Li, Et2O, (ii) /BRN= 385735/, (iii) P2O5 2: Pd-C / 350 °C View Scheme