2,2-二甲基-苯并二氢吡喃-4-酮合成路线 （共 66 条）
反应条件
nickel in ethanol
1 h; Ambient temperature;
参考文献
Sebok; Timar; Eszenyi; Patonay
Journal of Organic Chemistry, 1994 , vol. 59, # 21 p. 6318 - 6321
反应条件
tert.-butylhydroperoxide; 4C12H25O4S(1-)*Fe2O(4+)*10H2O in water
T=30°C; 50 h;
参考文献
Nagano, Takashi; Kobayashi, Shu
Chemistry Letters, 2008 , vol. 37, # 10 p. 1042 - 1043
反应条件
hydrogenchloride in chloroform; water; acetone; toluene
参考文献
Wakunaga Seiyaku Kabushiki Kaisha
Patent: US5208245 A1, 1993 ;
反应条件
pyrrolidine in acetone
参考文献
Hoechst Aktiengesellschaft
Patent: US5043344 A1, 1991 ;
反应条件
sodium hydroxide; hydrogen; nickel in ethanol
P=3800 Torr; 1 h; Ambient temperature; Yield given. Yields of byproduct given;
参考文献
Sebok; Timar; Eszenyi; Patonay
Journal of Organic Chemistry, 1994 , vol. 59, # 21 p. 6318 - 6321
反应条件
sodium hydroxide; hydrogen; nickel in ethanol
P=3800 Torr; 1 h; Ambient temperature; Yield given. Yields of byproduct given;
参考文献
Sebok; Timar; Eszenyi; Patonay
Journal of Organic Chemistry, 1994 , vol. 59, # 21 p. 6318 - 6321
反应条件
1: 94 percent / Et3N / CH2Cl2 / 0.58 h / -15 - 23 °C
2: 93 percent / formic acid; PPh3 / palladium(II) acetate / dimethylformamide / 0.83 h / 60 °C
View Scheme
参考文献
Koever, Jozsef; Antus, Sandor
Zeitschrift fur Naturforschung - Section B Journal of Chemical Sciences, 2005 , vol. 60, # 7 p. 792 - 796
反应条件
pyrrolidine in toluene
T=20°C; 24.2 h; Molecular sieveInert atmosphereReflux;
参考文献
Sheppard, Cody I.; Taylor, Jessica L.; Wiskur, Sheryl L.
Organic Letters, 2011 , vol. 13, # 15 p. 3794 - 3797
反应条件
amberlyst-15 in chloroform
2 h;
参考文献
Deagostino, Annamaria; Farina, Vittorio; Prandi, Cristina; Zavattaro, Chiara; Venturello, Paolo
European Journal of Organic Chemistry, 2006 , # 15 p. 3451 - 3456
反应条件
1: H2, NaOH / Raney-Ni / ethanol / 1 h / 3800 Torr / Ambient temperature
2: 98 percent / 1,4-diazabicyclo<2.2.2>octane / dimethylformamide / 2 h / Ambient temperature
3: 94 percent / N,N-dimethylaniline / 1 h / 200 °C
4: 94 percent / KOH / methanol / 1 h / Heating
5: Raney-Ni / ethanol / Ambient temperature
View Scheme
参考文献
Sebok; Timar; Eszenyi; Patonay
Journal of Organic Chemistry, 1994 , vol. 59, # 21 p. 6318 - 6321
