2,2-二甲基-苯并二氢吡喃-4-酮合成路线 （共 66 条）
反应条件
1: 36 percent / K2CO3 / Pd(PPh3)4 / tetrahydrofuran / 80 °C
2: 75 percent / Amberlyst-15 (R) / CHCl3 / 2 h
View Scheme
参考文献
Deagostino, Annamaria; Farina, Vittorio; Prandi, Cristina; Zavattaro, Chiara; Venturello, Paolo
European Journal of Organic Chemistry, 2006 , # 15 p. 3451 - 3456
反应条件
1: 36 percent / K2CO3 / Pd(PPh3)4 / tetrahydrofuran / 80 °C
2: 75 percent / Amberlyst-15 (R) / CHCl3 / 2 h
View Scheme
参考文献
Deagostino, Annamaria; Farina, Vittorio; Prandi, Cristina; Zavattaro, Chiara; Venturello, Paolo
European Journal of Organic Chemistry, 2006 , # 15 p. 3451 - 3456
反应条件
pyrrolidine in toluene
Heating;
参考文献
Kabbe, Hans-Joachim; Widdig, Arno
Angewandte Chemie, 1982 , vol. 94, # 4 p. 254 - 262
参考文献
Ramana, M. M. V.; Kudav, N. A.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1988 , vol. 27, # 1-12 p. 339 - 341
反应条件
1: 85 percent / Et3N / CH2Cl2 / 0.5 h / -15 - 23 °C
2: 75 percent / formic acid; Et3N; 1,3-bis(diphenylphosphanyl)propane / palladium(II) acetate / dimethylformamide / 0.5 h
View Scheme
参考文献
Koever, Jozsef; Antus, Sandor
Zeitschrift fur Naturforschung - Section B Journal of Chemical Sciences, 2005 , vol. 60, # 7 p. 792 - 796
反应条件
1: 94 percent / N,N-dimethylaniline / 1 h / 200 °C
2: 94 percent / KOH / methanol / 1 h / Heating
3: Raney-Ni / ethanol / Ambient temperature
View Scheme
参考文献
Sebok; Timar; Eszenyi; Patonay
Journal of Organic Chemistry, 1994 , vol. 59, # 21 p. 6318 - 6321
反应条件
1: 91 percent / N,N-dimethylaniline / 1 h / 200 °C
2: 48 percent / Raney-Ni / ethanol / 1 h / Ambient temperature
View Scheme
参考文献
Sebok; Timar; Eszenyi; Patonay
Journal of Organic Chemistry, 1994 , vol. 59, # 21 p. 6318 - 6321
反应条件
diethyl ether
anschliessend Behandeln mit wss. Ammoniumchlorid-Loesung;
参考文献
Wawzonek et al.
Journal of the American Chemical Society, 1954 , vol. 76, p. 1080
反应条件
nickel in ethanol
Ambient temperature;
参考文献
Sebok; Timar; Eszenyi; Patonay
Journal of Organic Chemistry, 1994 , vol. 59, # 21 p. 6318 - 6321
反应条件
aluminium trichloride
参考文献
Patonay, Tamas; Levai, Albert; Nemes, Csaba; Timar, Tibor; Toth, Gabor; Adam, Waldemar
Journal of Organic Chemistry, 1996 , vol. 61, # 16 p. 5375 - 5383
