1: benzyl azide With triphenylphosphine on polystyrene in tetrahydrofuran
T=20°C; Staudinger reaction; 4 h;
2: 4-bromomethyl-benzonitrile in tetrahydrofuran
T=20°C; 16 h;
3: With potassium hydroxide in methanol
T=65°C; 4 h; Further stages.;
1: With hydrogenchloride in diethyl ether
T=23°C; 1 h; Inert atmosphere;
2: With sodium hydrogencarbonate in methanol; water
T=23°C; 2 h; Inert atmosphere;
参考文献
Cheng, Chen; Brookhart, Maurice
Journal of the American Chemical Society, 2012 , vol. 134, # 28 p. 11304 - 11307
