N-[2-氨基-9-[(4S,5R)-4-羟基-5-(羟基甲基)四氢呋喃-2-基]-6-氧代-3H-嘌呤-8-基]-N-(9H-芴-2-基)乙酰胺合成路线 (共 3 条)
反应条件
sodium hydroxide; air T=75°C;
参考文献
Shibutani; Gentles; Iden; Johnson, Francis
Journal of the American Chemical Society, 1990 , vol. 112, # 14 p. 5667 - 5668
反应条件
dichloro-acetic acid in methanol; dichloromethane
Ambient temperature;
参考文献
Zhou, Yuanzhong; Chladek, Stanislav; Romano, Louis J.
Journal of Organic Chemistry, 1994 , vol. 59, # 3 p. 556 - 563
反应条件
hydrogen; palladium on activated charcoal
T=150°C; P=45003.6 - 60004.8 Torr; 3 h; extractive hydrogenation in the presence of DNA; Product distribution;
参考文献
Itani, Mohammad; Giese, Roger W.
Analytical Chemistry, 1994 , vol. 66, # 7 p. 1189 - 1197