4,5-二甲基-1,3-二氧杂环戊烯-2-酮合成路线 （共 13 条）
反应条件
chlorine in dichloromethane T=43 - 45°C; further solvents; Product distribution;
参考文献
Ikeda, Shoji; Takebe, Yasushi; Hirayama, Ryoichi; Sakamoto, Fumio; Iuchi, Koji; Tsukamoto, Goro
Chemical and Pharmaceutical Bulletin, 1988 , vol. 36, # 1 p. 394 - 397
反应条件
1: 80.8 percent / sodium bicarbonate, α,α'-azobisisobutyronitrile, Br2 / CCl4 / 1.08 h / 70 °C
2: 92 percent / potassium iodide / acetone / Ambient temperature
View Scheme
参考文献
Sakamoto; Ikeda; Tsukamoto
Chemical and Pharmaceutical Bulletin, 1984 , vol. 32, # 6 p. 2241 - 2248
反应条件
N-bromosuccinmide; azobisisobutyronitrile in tetrachloromethane
参考文献
NICOX S.A.; MERCK andamp; CO. INC.; ALMIRANTE, Nicoletta; MANDELLI, Valentino; NICOTRA, Alessia; BIONDI, Stefano; ONGINI, Ennio; SEBHAT, Iyassu
Patent: WO2010/15447 A1, 2010 ;
Location in patent: Page/Page column 50 ;
WO 2010/015447 A1
