(S)-(-)-1-苯丙胺合成路线 （共 55 条）
反应条件
ammonium hydroxide; hydrogen; 3percent Pt on activated carbon (F1082QHA/W3percent) modified with N-phenylacetyl-S-benzyl-L-cysteine ethyl ester in methanol T=55°C; P=22502.3 Torr; 17.3333 h; Product distribution / selectivity;
参考文献
Wolf, Dorit; Riermeier, Thomas; Drauz, Karlheinz; Weber, Christoph
Patent: US2010/105945 A1, 2010 ;
Location in patent: Page/Page column 4; 6-7 ;
反应条件
1: With [((R)-tol-binap)RuCl2(DMF)x]; ammonia; ammonium formate in methanol T=85°C; Leuckart-Wallach reaction; 21 h; 2: With hydrogenchloride in ethanol 1 h; Heating; Title compound not separated from byproducts;
参考文献
Xie, Ying; Pan, Hongjie; Xiao, Xiao; Li, Songlei; Shi, Yian
Organic and Biomolecular Chemistry, 2012 , vol. 10, # 45 p. 8960 - 8962,3
Title/Abstract Full Text Show Details
Xie, Ying; Pan, Hongjie; Xiao, Xiao; Li, Songlei; Shi, Yian
Organic and Biomolecular Chemistry, 2012 , vol. 10, # 45 p. 8960 - 8962
反应条件
hydrogen; palladium on activated charcoal in methanol; acetic acid T=20°C; 0.166667 h;
参考文献
Kawakami; Ohtake; Arakawa; Okachi; Imada; Murahashi
Bulletin of the Chemical Society of Japan, 2000 , vol. 73, # 11 p. 2423 - 2444
反应条件
Novozym 435 T=23°C; 24 h; Molecular sieveEnzymatic reaction; optical yield given as percent eeenantioselective reaction;
参考文献
Ditrich, Klaus
Synthesis, 2008 , # 14 SPEC. ISS. art. no. C01108SS, p. 2283 - 2287
反应条件
pyridoxal 5'-phosphate; recombinant ω-transaminase from Burkholderia vietnamiensis G4 in aq. phosphate buffer T=37°C; pH=7.4; 0.0833333 h; Enzymatic reaction; enantioselective reaction;
参考文献
Jiang, Jinju; Chen, Xi; Feng, Jinhui; Wu, Qiaqing; Zhu, Dunming
Journal of Molecular Catalysis B: Enzymatic, 2014 , vol. 100, p. 32 - 39
反应条件
6-(1,2:3,4-di-O-isopropylidene-α-D-galactopyranosyl) hydrogen phthalate in isopropyl alcohol Heating;
参考文献
Mereyala, Hari Babu; Fatima, Liyakat; Pola, Pallavi
Tetrahedron Asymmetry, 2004 , vol. 15, # 4 p. 585 - 587
反应条件
Gewinnung ueber das (in Aethanol schwer loesliche) Lg-Hydrogentartrat;
参考文献
DeWitt; Ingersoll
Journal of the American Chemical Society, 1951 , vol. 73, p. 5782
反应条件
sodium tetrahydroborate; (S)-valinol; zirconium tetrachloride 1) THF, r.t., 2) THF, r.t.; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Itsuno, Shinichi; Matsumoto, Takeshi; Sato, Daisuke; Inoue, Tsutomu
Journal of Organic Chemistry, 2000 , vol. 65, # 18 p. 5879 - 5881
反应条件
hydrogenchloride; palladium on activated charcoal in methanol P=3309.8 Torr; 48 h;
参考文献
Takahashi, Hiroshi; Suzuki, Yuji
Chemical & Pharmaceutical Bulletin, 1983 , vol. 31, # 12 p. 4295 - 4299
反应条件
sodium tetrahydroborate; (S)-valinol; zirconium tetrachloride 1) THF, r.t., 2) THF, r.t.; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Itsuno, Shinichi; Sakurai, Yoshiki; Shimizu, Koji; Ito, Koichi
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1990 , # 7 p. 1859 - 1863
