Alpha-(三氟甲基)二苯甲醇合成路线 （共 40 条）
反应条件
1-tert-butyl-4,4,4-tris(dimethylamino)-2,2-bis[tris(dimethylamino)-phosphoranylidenamino]-2Λ54Λ5-catenadi(phosphazene) in tetrahydrofuran; hexane T=-40°C; 3 h; Inert atmosphere; TimeReagent/catalyst;
参考文献
Zhang, Yuan; Fujiu, Motohiro; Serizawa, Hiroki; Mikami, Koichi
Journal of Fluorine Chemistry, 2013 , vol. 156, p. 367 - 371
反应条件
1: in N,N-dimethyl-formamide T=70°C; 1 h; Inert atmosphere; 2: With hydrogenchloride in water; N,N-dimethyl-formamide T=20°C;
参考文献
Levin, Vitalij V.; Dilman, Alexander D.; Belyakov, Pavel A.; Struchkova, Marina I.; Tartakovsky, Vladimir A.
Tetrahedron Letters, 2011 , vol. 52, # 2 p. 281 - 284
反应条件
potassium tert-butylate in N,N-dimethyl-formamide T=-50 - 20°C;
参考文献
Prakash, G. K. Surya; Hu, Jinbo; Olah, George A.
Organic Letters, 2003 , vol. 5, # 18 p. 3253 - 3256
反应条件
1: C9H16N2*C3H2F6O2 With potassium tert-butylate; tetrabutyl-ammonium chloride in N,N-dimethyl-formamide T=-30°C; 0.5 h; 2: benzophenone in N,N-dimethyl-formamide T=-30°C; 1.5 h;
参考文献
Riofski, Mark V.; Hart, Allison D.; Colby, David A.
Organic Letters, 2013 , vol. 15, # 1 p. 208 - 211
反应条件
hydrogen fluoride 5 h; Ambient temperature; Yield given;
参考文献
Ahvazi, Behzad C.; Crestini, Claudia; Argyropoulos, Dimitris S.
Journal of Agricultural and Food Chemistry, 1999 , vol. 47, # 1 p. 190 - 201
反应条件
1,1,1,3,3,3-hexamethyl-disilazane in N,N-dimethyl-formamide T=-50°C; 20 mF, Pb cathode;
参考文献
Shono; Kise; Oka
Tetrahedron Letters, 1991 , vol. 32, # 45 p. 6567 - 6570
反应条件
potassium tert-butylate in tetrahydrofuran; N,N-dimethyl-formamide T=20°C; 24 h;
参考文献
Jablonski, Lukas; Joubert, Jerome; Billard, Thierry; Langlois, Bernard R.
Synlett, 2003 , # 2 p. 230 - 232
反应条件
potassium tert-butylate in tetrahydrofuran; N,N-dimethyl-formamide T=20°C; 0.333333 h;
参考文献
Jablonski, Lukas; Billard, Thierry; Langlois, Bernard R.
Tetrahedron Letters, 2003 , vol. 44, # 5 p. 1055 - 1057
反应条件
SS-Phos; [RhCl(η2:η2-cycloocta-1,5-diene)]2; sodium hydroxide in water T=80°C; 24 h; Inert atmosphere;
参考文献
White, James R.; Price, Gareth J.; Plucinski, Pawel K.; Frost, Christopher G.
Tetrahedron Letters, 2009 , vol. 50, # 52 p. 7365 - 7368
反应条件
potassium tert-butylate in tetrahydrofuran T=0°C; 1 h;
参考文献
Inschauspe, David; Sortais, Jean-Baptiste; Billard, Thierry; Langlois, Bernard R.
Synlett, 2003 , # 2 p. 233 - 235
