1-苯基-2,3,4,9-四氢-1H-beta-咔啉合成路线 （共 50 条）
反应条件
1: 55 percent / polyphosphoric acid / CH2Cl2 2: 90 percent / NaBH4 / methanol / 0.5 h / 20 °C View Scheme
参考文献
Espinoza-Moraga, Marlene; Caballero, Julio; Gaube, Friedemann; Winckler, Thomas; Santos, Leonardo S.
Chemical Biology and Drug Design, 2012 , vol. 79, # 4 p. 594 - 599
反应条件
in acetonitrile 4 h; Heating;
参考文献
Hiemstra, H. C.; Bieraeugel, H.; Wijnberg, M.; Pandit, U. K.
Tetrahedron, 1983 , vol. 39, # 23 p. 3981 - 3986
反应条件
in tetrahydrofuran; diethyl ether T=-42°C; 1.5 h; Yield given;
参考文献
Kawate; Nakagawa; Yamazaki; Hirayama; Hino
Chemical and Pharmaceutical Bulletin, 1993 , vol. 41, # 2 p. 287 - 291
反应条件
(-)-Ipc2BCl in dichloromethane 63 h; Ambient temperature; Title compound not separated from byproducts;
参考文献
Kawate, Tomohiko; Nakagawa, Masako; Ogata, Koreharu; Hino, Tohru
Heterocycles, 1992 , vol. 33, # 2 p. 801 - 811
反应条件
in tetrahydrofuran; diethyl ether T=-78°C; 3 h; Yield given;
参考文献
Kawate; Nakagawa; Yamazaki; Hirayama; Hino
Chemical and Pharmaceutical Bulletin, 1993 , vol. 41, # 2 p. 287 - 291
反应条件
hydrogenchloride in N,N-dimethyl-formamide Heating;
参考文献
Singh, Harjit; Sarin, Rakesh; Singh, Kamaljit
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1988 , vol. 27, # 1-12 p. 132 - 134
反应条件
acetic acid 4 h; Heating;
参考文献
Singh, Harjit; Sarin, Rakesh
Journal of Chemical Research, Miniprint, 1988 , # 10 p. 2623 - 2640
反应条件
acetic acid 4 h; Heating;
参考文献
Singh, Harjit; Sarin, Rakesh
Journal of Chemical Research, Miniprint, 1988 , # 10 p. 2623 - 2640
反应条件
acetic acid 4 h; Heating;
参考文献
Singh, Harjit; Sarin, Rakesh
Journal of Chemical Research, Miniprint, 1988 , # 10 p. 2623 - 2640
反应条件
1: phosphorus oxychloride 2: sodium borohydride View Scheme
参考文献
Suckling, Colin J.; Murphy, John A.; Khalaf, Abedawn I.; Zhou, Sheng-ze; Lizos, Dimitris E.; van Nhien, Albert Nguyen; Yasumatsu, Hiroshi; McVie, Allan; Young, Louise C.; McCraw, Corinna; Waterman, Peter G.; Morris, Brian J.; Pratt, Judith A.; Harvey, Alan L.
Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 9 p. 2649 - 2655
