2,6-二甲基-4-甲氧基苯甲酸合成路线 （共 13 条）
反应条件
1: With n-butyllithium in tetrahydrofuran; hexanes T=-78°C; 0.833333 h; 2: With hydrogenchloride; water in tetrahydrofuran; hexanes T=0°C;
参考文献
Tachdjian, Catherine; Patron, Andrew P.; Adamski-Werner, Sara L.; Bakir, Farid; Chen, Qing; Darmohusodo, Vincent; Hobson, Stephen Terrence; Li, Xiaodong; Qi, Ming; Rogers, Daniel Harry; Rinnova, Marketa; Servant, Guy; Tang, Xiao-Qing; Zoller, Mark; Wallace, David; Xing, Amy; Gubernator, Klaus
Patent: US2005/84506 A1, 2005 ;
Location in patent: Page/Page column 97 ;
US 20050084506 A1
反应条件
diethyl ether; magnesium Eintragen des Reaktionsgemisches in festes Kohlendioxid;
参考文献
Fuson; Corse; Welldon
Journal of the American Chemical Society, 1941 , vol. 63, p. 2645
反应条件
chromium(VI) oxide; sulfuric acid; water in acetone 4 h; Ambient temperature;
参考文献
Bhattacharya, Kalyan K.; Pal, Panchanan; Ghosh, Kalpana; Sen, P. K.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1980 , vol. 19, # 3 p. 191 - 194
反应条件
Boc-Phe-OH; palladium diacetate; lithium carbonate; silver carbonate; p-benozquinone in tert-butyl alcohol T=90°C; 12 h; Inert atmosphere; Reagent/catalyst;
参考文献
Rosen, Brandon R.; Simke, Leah R.; Thuy-Boun, Peter S.; Dixon, Darryl D.; Yu, Jin-Quan; Baran, Phil S.
Angewandte Chemie - International Edition, 2013 , vol. 52, # 28 p. 7317 - 7320
Angew. Chem., 2013 , vol. 125, # 28 p. 7458 - 7461,4
反应条件
1: 85 percent / NaOH / H2O / 2 h / 10 °C 2: 8 percent / CrO3, conc. H2SO4, water / acetone / 4 h / Ambient temperature View Scheme
参考文献
Bhattacharya, Kalyan K.; Pal, Panchanan; Ghosh, Kalpana; Sen, P. K.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1980 , vol. 19, # 3 p. 191 - 194
反应条件
potassium permanganate; acetone
参考文献
Burawoy; Chamberlain
Journal of the Chemical Society, 1949 , p. 624
反应条件
water in acetone T=-20°C; Rate constant;
参考文献
Ugi,I.; Beck,F.
Chemische Berichte, 1961 , vol. 94, p. 1839 - 1850
反应条件
1: aqueous NaOH 2: acetone; aqueous potassium permanganate View Scheme
参考文献
Burawoy; Chamberlain
Journal of the Chemical Society, 1949 , p. 624
反应条件
1) diazotation; Multistep reaction;
参考文献
Yates, Keith; Mandrapilias, George
Journal of Organic Chemistry, 1980 , vol. 45, # 19 p. 3892 - 3902
反应条件
dioxane - water; potassium chloride T=25°C; dependence on pH of the hydrolysis; MechanismRate constant;
参考文献
Thea, Sergio; Guanti, Giuseppe; Kashefi-Naini, Nasrin; Williams, Andrew
Journal of the Chemical Society, Chemical Communications, 1983 , # 9 p. 529 - 530
