5-((四氢吡喃-2-基)氧基)-1-溴戊烷合成路线 （共 41 条）
反应条件
copper(l) iodide in tetrahydrofuran 48 h; Ambient temperature; Yield given;
参考文献
Buergi, Christoph; Liu, Gui; Rueedi, Peter
Helvetica Chimica Acta, 1993 , vol. 76, p. 1901 - 1915
反应条件
1: 1.) Mg / 2.) Li2CuCl4 / 1.) Et2O, reflux, 2 h, 2.) THF, 0 deg C, 3 h 2: 1.) 9-BBN, 2.) 6 M aq. NaOH, 30percent H2O2 / 1.) THF, 30 deg C, 6 h, 2.) 40 deg C, 1 h View Scheme
参考文献
Heiser, Ulrich F.; Dobner, Bodo
Journal of the Chemical Society - Perkin Transactions 1, 1997 , # 6 p. 809 - 815
反应条件
[2,2']bipyridinyl; copper(l) iodide; toluene-4-sulfonic acid; magnesium 1.) THF, HF, 20 deg C, 2 h, 20 deg C, 16 h, reflux, 4 h, 2.) EtOH, rt, 24 h; Yield given. Multistep reaction;
参考文献
Odinokov; Vakhidov; Shakhmaev; Zorin
Chemistry of Natural Compounds, 1996 , vol. 32, # 6 p. 912 - 914
反应条件
1: 1.) BuLi / 1.) THF, hexane, 2 h, -20 deg C, 2.) 30 min, -78 degC 2: LiAlH4 / diethyl ether / 1 h / 0 °C 3: p-toluenesulfonic acid / methanol; H2O / 3 h / Heating View Scheme
参考文献
Canevet; Roeder; Vostrowsky; Bestmann
Chemische Berichte, 1980 , vol. 113, # 3 p. 1115 - 1120
反应条件
Multistep reaction; A Stereoselective Synthesis of (E)-Olefinic Sex Pheromones of Moths; var. allyl diethyl phosphonates, var. ω-bromoalkyltetrahydropyranyl ethers; Product distribution;
参考文献
Canevet; Roeder; Vostrowsky; Bestmann
Chemische Berichte, 1980 , vol. 113, # 3 p. 1115 - 1120
反应条件
copper(l) iodide in tetrahydrofuran 48 h; Ambient temperature; Yield given;
参考文献
Buergi, Christoph; Liu, Gui; Rueedi, Peter
Helvetica Chimica Acta, 1993 , vol. 76, p. 1901 - 1915
参考文献
Mansurova, Madina; Klusak, Vojtech; Nesnerova, Petra; Muck, Alexander; Doubsky, Jan; Svatos, Ales
Tetrahedron, 2009 , vol. 65, # 5 p. 1069 - 1076
反应条件
2: CBr3, PPh3
View Scheme
参考文献
Smallheer, Joanne M.; McHugh, Robert J.; Chang, Chong-Hwan; Kaltenbach III, Robert F.; Worley, Tabitha V.; Klabe, Ronald M.; Bacheler, Lee T.; Rayner, Marlene M.; Erickson-Viitanen, Susan; Seitz, Steven P.
Bioorganic and Medicinal Chemistry Letters, 1997 , vol. 7, # 11 p. 1365 - 1370
反应条件
1: 36 percent / aq. HBr / 22 h / 80 °C
2: 96 percent / conc. HCl / 2.5 h / 20 °C
View Scheme
参考文献
Mueller, Silvia; Schmidt, Richard R.
Advanced Synthesis and Catalysis, 2000 , vol. 342, # 8 p. 779 - 784
反应条件
1: 2N NaOH / ethanol
2: p-TsOH
View Scheme
参考文献
Tomida, Ichiro; Mayesawa, Tsuneaki
Bioscience, Biotechnology, and Biochemistry, 1992 , vol. 56, # 12 p. 1962 - 1965
