苯丙氨酰-苯丙氨酸甲酯盐酸盐合成路线 （共 9 条）
反应条件
hydrogenchloride in ethyl acetate
T=0°C; 2 h;
参考文献
Tamiaki; Kiyomori; Maruyama
Bulletin of the Chemical Society of Japan, 1994 , vol. 67, # 9 p. 2478 - 2486
反应条件
1: 92 percent / Et3N, DCC / CH2Cl2 / 0 - 20 °C
2: 100 percent / HCl / ethyl acetate / 2 h / 0 °C
View Scheme
参考文献
Tamiaki; Kiyomori; Maruyama
Bulletin of the Chemical Society of Japan, 1994 , vol. 67, # 9 p. 2478 - 2486
反应条件
acetyl chloride
T=0 - 20°C;
参考文献
Skaat, Hadas; Chen, Ravit; Grinberg, Igor; Margel, Shlomo
Biomacromolecules, 2012 , vol. 13, # 9 p. 2662 - 2670
反应条件
1: 92 percent / Et3N, DCC / CH2Cl2 / 0 - 20 °C
2: 100 percent / HCl / ethyl acetate / 2 h / 0 °C
View Scheme
参考文献
Tamiaki; Kiyomori; Maruyama
Bulletin of the Chemical Society of Japan, 1994 , vol. 67, # 9 p. 2478 - 2486
反应条件
1: 72 percent / 1 N aq. NaOH / 22 °C / 1-3 h
2: 82 percent / triethylamine, 1,3-dicyclohexylcarbodiimide / CH2Cl2 / 1 h / 0 °C
3: 3 N aq. HCl / dioxane / 10 h / Ambient temperature
View Scheme
参考文献
Gorbunova; Gerus; Galushko; Kukhar
Synthesis, 1991 , # 3 p. 207 - 209
反应条件
hydrogenchloride in 1,4-dioxane
10 h; Ambient temperature;
参考文献
Gorbunova; Gerus; Galushko; Kukhar
Synthesis, 1991 , # 3 p. 207 - 209
反应条件
1: 82 percent / triethylamine, 1,3-dicyclohexylcarbodiimide / CH2Cl2 / 1 h / 0 °C
2: 3 N aq. HCl / dioxane / 10 h / Ambient temperature
View Scheme
参考文献
Gorbunova; Gerus; Galushko; Kukhar
Synthesis, 1991 , # 3 p. 207 - 209
反应条件
1: 100 percent / HCl / ethyl acetate / 2 h / 0 °C
2: 92 percent / Et3N, DCC / CH2Cl2 / 0 - 20 °C
3: 100 percent / HCl / ethyl acetate / 2 h / 0 °C
View Scheme
参考文献
Tamiaki; Kiyomori; Maruyama
Bulletin of the Chemical Society of Japan, 1994 , vol. 67, # 9 p. 2478 - 2486
反应条件
1: 87 percent / HOBt, N-methylmorpholine
2: 98 percent / 6N HCl / dioxane / 2 h
View Scheme
参考文献
Kessler, Horst; Mueller, Arndt
Liebigs Annalen der Chemie, 1986 , # 10 p. 1687 - 1704
