(9ci)-5-氯-1-甲基-1H-苯并咪唑-2-甲醇合成路线 （共 4 条）
参考文献
PFIZER INC.
Patent: WO2004/74270 A2, 2004 ;
Location in patent: Page 131 ;
反应条件
tetrabutylammomium bromide; potassium hydroxide in tetrahydrofuran
T=0°C;
参考文献
Eom, Young Woo; Oh, Sangtae; Woo, Ho Bum; Ham, Jungyeob; Ahn, Chan Mug; Lee, Seokjoon
Bulletin of the Korean Chemical Society, 2013 , vol. 34, # 4 p. 1272 - 1274
反应条件
1: hydrogenchloride / water / 6 h / Reflux
2: tetrabutylammomium bromide; potassium hydroxide / tetrahydrofuran / 0 °C
View Scheme
参考文献
Woo, Ho Bum; Eom, Young Woo; Park, Kyu-Sang; Ham, Jungyeob; Ahn, Chan Mug; Lee, Seokjoon
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 2 p. 933 - 936
反应条件
ethanol; nickel
Hydrogenation.Erhitzen des Reaktionsprodukts mit Glykolsaeure in wss. HCl;
参考文献
Feitelson et al.
Journal of the Chemical Society, 1952 , p. 2389,2393
