2-氯-3-N,N-二乙基吡啶羧酰胺合成路线 （共 5 条）
反应条件
thionyl chloride; toluene in dichloromethane
参考文献
Sanofi
Patent: US5079363 A1, 1992 ;
反应条件
in dichloromethane
0.5 h; T < 20 deg C; Yield given;
参考文献
Dormoy, Jean-Robert; Heymes, Alain
Tetrahedron, 1993 , vol. 49, # 14 p. 2885 - 2914
反应条件
in dichloromethane
T=0 - 20°C;
参考文献
ArQule, Inc.
Patent: US2010/249108 A1, 2010 ;
Location in patent: Page/Page column 75-76 ;
反应条件
trichlorophosphate
T=110°C; 2 h;
参考文献
Yamanaka, Hiroshi; Araki, Tomio; Sakamoto, Takao
Chemical and Pharmaceutical Bulletin, 1988 , vol. 36, p. 2244 - 2247
反应条件
1: SOCl2 / 3 h / Heating
2: CH2Cl2 / 0.5 h / T < 20 deg C
View Scheme
参考文献
Dormoy, Jean-Robert; Heymes, Alain
Tetrahedron, 1993 , vol. 49, # 14 p. 2885 - 2914
