2-三甲基硅氧基-1,3-丁二烯合成路线 （共 28 条）
反应条件
potassium carbonate 1.) C6H6, 15 H, reflux, 2.) CH3OH; Yield given. Multistep reaction;
参考文献
Jung, Michael E.; Shishido, Kozo; Light, Lynn; Davis, Leonard
Tetrahedron Letters, 1981 , vol. 22, # 46 p. 4607 - 4610
反应条件
methanol 1.) toluene, reflux, 45 h, 2.) 2 h; Yield given. Multistep reaction;
参考文献
Jung,M.E.; Mccombs,C.A.; Takeda,Y.
Journal of the American Chemical Society, 1981 , vol. 103, p. 6677
反应条件
hydrogenchloride 1.) 150 deg C, 72 h; Multistep reaction;
参考文献
Journal of Organic Chemistry, , vol. 47, # 11 p. 2051 - 2055
反应条件
1: With CoBr2(1,2-bis(diphenylphosphino)ethane); zinc(II) iodide; zinc in dichloromethane T=20°C; Diels-Alder Cycloaddition; 16 h; Inert atmosphere; 2: With 2,3-dicyano-5,6-dichloro-p-benzoquinone in toluene T=20°C; 1.5 h; Inert atmosphere; Overall yield = 79 percent; Overall yield = 90.7 mg;
参考文献
Puenner, Florian; Schieven, Justin; Hilt, Gerhard
Organic Letters, 2013 , vol. 15, # 18 p. 4888 - 4891
反应条件
hydrogenchloride; zinc(II) chloride
1.) acetonitrile, 4 h, 50 deg C; 2.) 10 min; Yield given. Multistep reaction;
参考文献
Vacca, J. P.
Tetrahedron Letters, 1985 , vol. 26, # 10 p. 1277 - 1280
反应条件
Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Ramachary, Dhevalapally B.; Narayana, Vidadala V.; Prasad, M. Shiva; Ramakumar, Kinthada
Organic and Biomolecular Chemistry, 2009 , vol. 7, # 17 p. 3372 - 3378
反应条件
toluene-4-sulfonic acid
1.) toluene, reflux, 36 h, 2.) benzene, reflux (Dean-Stark), 6 h; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Audrain, Helene; Skrydstrup, Troels; Ulibarri, Gerardo; Riche, Claude; Chiaroni, Angele; Grierson, David S.
Tetrahedron, 1994 , vol. 50, # 5 p. 1469 - 1502
反应条件
hydroquinone in toluene
24 h; Heating;
参考文献
Rigby, James H.; Kotnis, Atul; Kramer, James
Journal of Organic Chemistry, 1990 , vol. 55, # 17 p. 5078 - 5088
反应条件
N-bromosuccinmide
1) THF, r.t., 2 h, 2) THF, r.t., 2 h; Yield given. Multistep reaction;
参考文献
Lueoend, Rainer M.; Walker, Josef; Neier, Reinhard W.
Journal of Organic Chemistry, 1992 , vol. 57, # 18 p. 5005 - 5013
反应条件
1: in xylenes
T=130°C;
2: With hydrogenchloride in tetrahydrofuran; water; xylenes
T=50°C;
参考文献
MERCK SHARP and DOHME LIMITED; MERCK and CO., INC.
Patent: WO2004/13090 A1, 2004 ;
Location in patent: Page 12-13 ;
