3-环丙基-1,3-二氢咪唑并[4,5-b]吡啶-2-酮合成路线 （共 3 条）
反应条件
in tetrahydrofuran
2.5 h; Heating / reflux;
参考文献
ARROW THERAPEUTICS LIMITED
Patent: WO2005/89771 A1, 2005 ;
Location in patent: Page/Page column 40 ;
WO 2005/089771 A1
反应条件
1.1: NaHMDS / tetrahydrofuran / 0.17 h / -10 °C
1.2: 81 percent / tetrahydrofuran / 0.5 h
2.1: t-BuONa; XantPhos / Pd2(dba)3 / Heating
View Scheme
参考文献
Scott, Jeremy P.
Synlett, 2006 , # 13 p. 2083 - 2086
反应条件
9,9-dimethyl-4,5-bis(diphenyl-phosphino)xanthene; sodium t-butanolate; tris(dibenzylideneacetone)dipalladium (0)
Heating;
参考文献
Scott, Jeremy P.
Synlett, 2006 , # 13 p. 2083 - 2086
