5-苯基噁唑-4-甲酸甲酯合成路线 （共 7 条）
反应条件
1: 80 percent / HCl 2: 92 percent / HCl View Scheme
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 32, # 7 p. 2536 - 2543
参考文献
Journal of Medicinal Chemistry, , vol. 29, # 3 p. 333 - 341
参考文献
Suzuki,M. et al.
Journal of Organic Chemistry, 1973 , vol. 38, p. 3571 - 3575
反应条件
triethylamine in tetrahydrofuran
T=20°C; 48 h;
参考文献
Nissan Chemical Industries, Ltd.
Patent: EP1650185 A1, 2006 ;
Location in patent: Page/Page column 20-21 ;
反应条件
P(MeNCH2CH2)3N in tetrahydrofuran
1.) 5 deg C, 15 min, 2.) r.t., 30 min;
参考文献
Tang; Verkade
Journal of Organic Chemistry, 1994 , vol. 59, # 25 p. 7793 - 7802
反应条件
sodium hydride in N,N-dimethyl-formamide; mineral oil
T=0 - 24°C; 24 h;
参考文献
Shao, Pan-Lin; Liao, Jia-Yu; Ho, Yee Ann; Zhao, Yu
Angewandte Chemie - International Edition, 2014 , vol. 53, # 21 p. 5435 - 5439
Angew. Chem., 2014 , vol. 126, # 21 p. 5539 - 5543
反应条件
diphenyl phosphoryl azide; potassium carbonate in N,N-dimethyl-formamide
1) 0-5 deg C, 2 hr, 2) room temp., 14 hr;
参考文献
Hamada, Yasumasa; Shioiri, Takayuki
Tetrahedron Letters, 1982 , vol. 23, # 2 p. 235 - 236
