二乙基(苯基硫代甲基)磷酸酯合成路线 （共 43 条）
反应条件
1: thiophenol With sodium hydride in tetrahydrofuran; mineral oil T=0°C; 0.5 h; Inert atmosphere; 2: iodomethylphosphonic acid diethyl ester in tetrahydrofuran; mineral oil T=0°C; 12 h; Inert atmosphere;
参考文献
Yang, Peng-Yu; Wang, Min; He, Cynthia Y.; Yao, Shao Q.
Chemical Communications, 2012 , vol. 48, # 6 p. 835 - 837
参考文献
Blumenkopf, Todd A.
Synthetic Communications, 1986 , vol. 16, # 2 p. 139 - 148
反应条件
Tebbe reagent in tetrahydrofuran T=-40 - 0°C; Reduction; Deoxygenation; 4 h;
参考文献
Nicolaou; Koumbis, Alexandros E.; Snyder, Scott A.; Simonsen, Klaus B.
Angewandte Chemie (International Edition in English), 2000 , vol. 39, # 14 p. X2529-2533
反应条件
caesium carbonate in N,N-dimethyl-formamide T=20°C;
参考文献
Woo, Seo Yeon; Kim, Ji Hyun; Moon, Mi Kyeong; Han, Se-Hee; Yeon, Seul Ki; Choi, Ji Won; Jang, Bo Ko; Song, Hyo Jung; Kang, Yong Gu; Kim, Jin Woo; Lee, Jaeick; Kim, Dong Jin; Hwang, Onyou; Park, Ki Duk
Journal of Medicinal Chemistry, 2014 , vol. 57, # 4 p. 1473 - 1487
反应条件
1: formaldehyd; thiophenol With hydrogenchloride in water; toluene T=50°C; 1 h; 2: triethyl phosphite T=130°C; 16 h;
参考文献
Bournaud, Chloee; Marchal, Estelle; Quintard, Adrien; Sulzer-Mosse, Sarah; Alexakis, Alexandre
Tetrahedron Asymmetry, 2010 , vol. 21, # 13-14 p. 1666 - 1673
反应条件
2,2'-azo-bisisobutyronitrile; tri-n-butyl-tin hydride in toluene 1 h; Heating;
参考文献
Balczewski,Piotr
Phosphorus, Sulfur and Silicon and the Related Elements, 1995 , vol. 104, # 14 p. 113 - 122
参考文献
FMC Corporation
Patent: US4200644 A1, 1980 ;
反应条件
triphenylphosphine; diethylazodicarboxylate in benzene 48 h; Ambient temperature;
参考文献
Gajda, Tadeusz
Synthesis, 1988 , # 4 p. 327 - 328
反应条件
1: 99 percent / N-chlorosuccinimide / CCl4 / 11 h / Ambient temperature 2: 73 percent / 48 h / 120 °C View Scheme
参考文献
Zhang, Yan; Wu, Yikang
Chinese Journal of Chemistry, 2010 , vol. 28, # 9 p. 1635 - 1639
反应条件
2,2'-azo-bisisobutyronitrile; tri-n-butyl-tin hydride in toluene 1 h; Heating;
参考文献
Balczewski,Piotr
Phosphorus, Sulfur and Silicon and the Related Elements, 1995 , vol. 104, # 14 p. 113 - 122
