1-(2'-氯-联苯-4-基)-乙酮合成路线 （共 8 条）
反应条件
sodium hypobromide in 1,4-dioxane
参考文献
Byron,D.J. et al.
Journal of the Chemical Society [Section] C: Organic, 1966 , p. 840 - 845
反应条件
1.1: Zn[N(SiMe3)2]2; tri-tert-butyl phosphine; lithium chloride; bis(dibenzylideneacetone)-palladium(0) / tetrahydrofuran / Inert atmosphere 1.2: Inert atmosphere 2.1: sodium azide; acetic acid; sodium nitrite / water / 0.5 h / 0 - 20 °C / Inert atmosphere 3.1: anhydrous xylene / 150 °C / Inert atmosphere; sealed tube View Scheme
参考文献
Ullah, Ehsan; McNulty, James; Robertson, Al
European Journal of Organic Chemistry, 2012 , # 11 p. 2127 - 2131
反应条件
tris-(dibenzylideneacetone)dipalladium(0); caesium carbonate; (Me)CgPPh in toluene
T=70°C; Suzuki coupling; Inert atmosphere; chemoselective reaction;
参考文献
Ullah, Ehsan; McNulty, James; Robertson, Al
European Journal of Organic Chemistry, 2012 , # 11 p. 2127 - 2131
反应条件
potassium phosphate; palladium diacetate in water; N,N-dimethyl-formamide
T=20°C; Suzuki-Miyaura cross-coupling; 3 h;
参考文献
Antelo Miguez, Jose M.; Adrio, Luis Angel; Sousa-Pedrares, Antonio; Vila, Jose M.; Hii, King Kuok
Journal of Organic Chemistry, 2007 , vol. 72, # 20 p. 7771 - 7774
反应条件
(R,R)-N,N'-bis[(2-fluorophenyl)methyl]-1,2-cyclohexanediamine PdCl2 complex; potassium carbonate in N,N-dimethyl-formamide
T=120°C; Suzuki coupling; 24 h; Aerobic conditions;
参考文献
Kylmaelae, Tuula; Kuuloja, Noora; Xu, Youjun; Rissanen, Kari; Franzen, Robert
European Journal of Organic Chemistry, 2008 , # 23 p. 4019 - 4024
反应条件
aluminium trichloride in nitrobenzene
参考文献
Byron,D.J. et al.
Journal of the Chemical Society [Section] C: Organic, 1966 , p. 840 - 845
参考文献
Allen and Hanburys Limited
Patent: US3979468 A1, 1976 ;
参考文献
Eli Lilly and Company
Patent: US3975543 A1, 1976 ;
