(2R)-A-[(1,3-二氢-1,3-二氧代-2H-异吲哚-2-基)氧基]-丁酸-1,1-二甲基乙酯合成路线 （共 6 条）
反应条件
trifluoroacetic acid in dichloromethane T=20°C; Cooling with ice;
参考文献
Yang, Dan; Liu, Guo-Jun; Hao, Yu; Li, Wei; Dong, Ze-Min; Zhang, Dan-Wei; Zhu, Nian-Yong
Chemistry - An Asian Journal, 2010 , vol. 5, # 6 p. 1356 - 1363
反应条件
triphenylphosphine; diethylazodicarboxylate in tetrahydrofuran
参考文献
Yang; Li; Ng; Yan; Qu; Wu
Journal of Organic Chemistry, 2001 , vol. 66, # 22 p. 7303 - 7312
反应条件
1: aq. HCl; NaNO2 / 6 h / 0 °C
2: 4 h / 60 °C
3: DMAP; DCC / CH2Cl2 / 12 h / 20 °C
4: K2CO3 / methanol; H2O / 12 h / 20 °C
5: 75 percent / DEAD; PPh3 / tetrahydrofuran
View Scheme
参考文献
Yang; Li; Ng; Yan; Qu; Wu
Journal of Organic Chemistry, 2001 , vol. 66, # 22 p. 7303 - 7312
反应条件
1: 4 h / 60 °C
2: DMAP; DCC / CH2Cl2 / 12 h / 20 °C
3: K2CO3 / methanol; H2O / 12 h / 20 °C
4: 75 percent / DEAD; PPh3 / tetrahydrofuran
View Scheme
参考文献
Yang; Li; Ng; Yan; Qu; Wu
Journal of Organic Chemistry, 2001 , vol. 66, # 22 p. 7303 - 7312
反应条件
1: DMAP; DCC / CH2Cl2 / 12 h / 20 °C
2: K2CO3 / methanol; H2O / 12 h / 20 °C
3: 75 percent / DEAD; PPh3 / tetrahydrofuran
View Scheme
参考文献
Yang; Li; Ng; Yan; Qu; Wu
Journal of Organic Chemistry, 2001 , vol. 66, # 22 p. 7303 - 7312
反应条件
1: K2CO3 / methanol; H2O / 12 h / 20 °C
2: 75 percent / DEAD; PPh3 / tetrahydrofuran
View Scheme
参考文献
Yang; Li; Ng; Yan; Qu; Wu
Journal of Organic Chemistry, 2001 , vol. 66, # 22 p. 7303 - 7312
