2-(2-氨基苯甲酰)吡啶合成路线 （共 17 条）
反应条件
1.1: PhLi; diisopropylamine / tetrahydrofuran / 1 h / -40 °C 1.2: 75 percent / 0.75 h / -70 °C 2.1: 86 percent / CrO3 / acetone / 3 h / -30 - 20 °C 3.1: 56 percent / aq. NH4OH / 110 °C View Scheme
参考文献
Bioorganic and medicinal chemistry letters, , vol. 12, # 24 p. 3573 - 3577
反应条件
1: 1.) LDA / 1.) THF, -70 deg C, 4 h, 2.) THF, -70 deg C, 1 h 2: 82 percent / CrO3 / acetone / 3 h 3: 90 percent / NH3 / H2O / Heating View Scheme
参考文献
Journal of Organometallic Chemistry, , vol. 215, # 2 p. 139 - 150
反应条件
1: 82 percent / CrO3 / acetone / 3 h 2: 90 percent / NH3 / H2O / Heating View Scheme
参考文献
Journal of Organometallic Chemistry, , vol. 215, # 2 p. 139 - 150
反应条件
in pentan-1-ol; acetic acid 2.5 h; Heating;
参考文献
Sollhuber-Kretzer; Troschutz
Archiv der Pharmazie, 1982 , vol. 315, # 9 p. 783 - 790
反应条件
diphenyl-phosphinic acid; triethylamine 1.) benzene, reflux, 1 h, 2.) H2O, 1 h, heating; Yield given. Multistep reaction;
参考文献
Archiv der Pharmazie, , vol. 315, # 9 p. 783 - 790
反应条件
1: With methanol; ammonia 2: With methanol Reflux;
参考文献
Tetrahedron Letters, , vol. 53, # 9 p. 1033 - 1035
反应条件
potassium hydroxide; hydrazine hydrate in ethylene glycol T=200°C; Wolf-Kishner reduction; 2 h;
参考文献
Andres, J Ignacio; Alonso, Jose M; Fernandez, Javier; Iturrino, Laura; Martinez, Pedro; Meert, Theo F; Sipido, Victor K
Bioorganic and medicinal chemistry letters, 2002 , vol. 12, # 24 p. 3573 - 3577
