toluene-4-sulfonamide in toluene T=120°C; 12 h; Inert atmosphere; optical yield given as percent de;

1: 4-ClC6H4CH2NHPh With 2,3-dicyano-5,6-dichloro-p-benzoquinone in N,N-dimethyl-formamide T=20°C; 0.0833333 h; Inert atmosphere; 2: 2-Methyl quinoline in N,N-dimethyl-formamide T=70°C; 24 h; Inert atmosphere; diastereoselective reaction;

in 1,3,5-trimethyl-benzene T=140°C; 12 h; Inert atmosphere; optical yield given as percent de;