4-(3-甲氧基苯基)-4-氧代丁酸合成路线 (共 13 条)
反应条件
hydrogenchloride; amalgamated zinc
参考文献
Thompson
Journal of the Chemical Society, 1932 , p. 2310,2313
Full Text Show Details
Martin
Journal of the American Chemical Society, 1936 , vol. 58, p. 1438,1439
Org. Reactions, 1942 , vol. 1, p. 155,167
Full Text Show Details
Chuang; Huang
Chemische Berichte, 1936 , vol. 69, p. 1505,1507
反应条件
hydrazine hydrate in ethanol
参考文献
Journal of Enzyme Inhibition and Medicinal Chemistry, , vol. 28, # 3 p. 552 - 559
反应条件
1: amalgamated zinc; aqueous hydrochloric acid 2: concentrated sulfuric acid View Scheme
参考文献
Thompson
Journal of the Chemical Society, 1932 , p. 2310,2313
反应条件
1: ethyl (3-methoxybenzoyl)acetate With sodium hydride in tetrahydrofuran
0.333333 h;
2: ethyl bromoacetate in tetrahydrofuran
5 h;
3: With water in tetrahydrofuran; methanol
2 h;
参考文献
EPIX DELAWARE, INC.
Patent: WO2007/47394 A2, 2007 ;
Location in patent: Page/Page column 64 ;
WO 2007/047394 A2
反应条件
1: sulfuric acid; nitric acid / <0
2: ammonium hydrogensulfide
3: aqueous sulfuric acid / Diazotization
4: aq. NaOH solution / anschliessendes Erhitzen
View Scheme
参考文献
Martin
Journal of the American Chemical Society, 1936 , vol. 58, p. 1438,1439
Org. Reactions, 1942 , vol. 1, p. 155,167
反应条件
1: ammonium hydrogensulfide
2: aqueous sulfuric acid / Diazotization
3: aq. NaOH solution / anschliessendes Erhitzen
View Scheme
参考文献
Martin
Journal of the American Chemical Society, 1936 , vol. 58, p. 1438,1439
Org. Reactions, 1942 , vol. 1, p. 155,167
反应条件
1: aqueous sulfuric acid / Diazotization
2: aq. NaOH solution / anschliessendes Erhitzen
View Scheme
参考文献
Martin
Journal of the American Chemical Society, 1936 , vol. 58, p. 1438,1439
Org. Reactions, 1942 , vol. 1, p. 155,167
Full Text Show Details
Chuang; Huang
Chemische Berichte, 1936 , vol. 69, p. 1505,1507
反应条件
sodium hydroxide
anschliessendes Erhitzen;
参考文献
Martin
Journal of the American Chemical Society, 1936 , vol. 58, p. 1438,1439
Org. Reactions, 1942 , vol. 1, p. 155,167
Full Text Show Details
Chuang; Huang
Chemische Berichte, 1936 , vol. 69, p. 1505,1507
参考文献
Dauben; Collette
Journal of the American Chemical Society, 1959 , vol. 81, p. 967,970
参考文献
Knott
Journal of the Chemical Society, 1947 , p. 1196,1200