1-(2-乙基丁基)环己烷羧酸合成路线 （共 13 条）
反应条件
in tetrahydrofuran; cyclohexane; water
参考文献
Japan Tobacco Inc.
Patent: US6426365 B1, 2002 ;
反应条件
1.1: diethylamine; methyl-magnesium chloride / tetrahydrofuran / 5 h / 45 - 70.2 °C / Inert atmosphere
1.2: 15 - 60 °C
2.1: water; sulfuric acid / 2.25 h / 105 °C / Inert atmosphere
3.1: water; sulfuric acid; nitrosyl-sulphuric acid / 2 h / 50 - 64 °C / Inert atmosphere
View Scheme
参考文献
Harnett, Gerard John; Hayes, John; Reents, Reinhard; Smith, Dennis A.; Walsh, Andrew
Patent: US2012/71683 A1, 2012 ;
反应条件
1.1: diethylamine; methyl-magnesium chloride / tetrahydrofuran / 5 h / 45 - 70.2 °C / Inert atmosphere
1.2: 15 - 60 °C
2.1: water; sulfuric acid / 2.25 h / 105 °C / Inert atmosphere
3.1: water; sulfuric acid; nitrosyl-sulphuric acid / 2 h / 50 - 64 °C / Inert atmosphere
View Scheme
参考文献
Harnett, Gerard John; Hayes, John; Reents, Reinhard; Smith, Dennis A.; Walsh, Andrew
Patent: US2012/71683 A1, 2012 ;
