1.1: triethylamine / copper(l) iodide; bis-triphenylphosphine-palladium(II) chloride / tetrahydrofuran / 1 h / 0 - 20 °C 2.1: potassium tert-butylate / tert-butyl alcohol / 1 h / 85 °C 3.1: AlCl3, aluminium chloride / dichloromethane / 0.83 h 3.2: 18 h View Scheme

1.1: triethylamine / copper(l) iodide; bis-triphenylphosphine-palladium(II) chloride / tetrahydrofuran / 1 h / 0 - 20 °C 2.1: potassium tert-butylate / tert-butyl alcohol / 1 h / 85 °C 3.1: AlCl3, aluminium chloride / dichloromethane / 0.83 h 3.2: 18 h 4.1: sodium hydroxide; N-benzyl-N,N,N-triethylammonium chloride / dichloromethane / 1.33 h / 0 - 20 °C View Scheme

copper(l) iodide; tetrakis(triphenylphosphine) palladium(0); triethylamine in tetrahydrofuran T=20°C; Sonogashira Cross-Coupling; Inert atmosphere;