反应条件
1: 98 percent / NaOH / methanol; H2O / 8 h / Heating
2: 1.) aq. sodium hydroxide 2.) oxalyl chloride, pyridine / 1.) 95percent ethanol 2.) benzene, room temp., 3 h
3: 1.) diisopropylamide, n-butyllithium / 1.) THF, -78 deg C, 1 h 2.) THF, -78 deg C, 4 h
4: NaOH / H2O; methanol / 3 h / Heating
5: 20percent HCl / 40 °C
6: 100 percent / H2 / 10percent Pd/C / ethyl acetate / 0.5 h
7: 1.) cupric acetate, pyridine, lead tetraacetate 2.) p-toluenesulfonic acid / 1.) benzene, room temp., 2 h, then 80 deg C, 1 h 2.) benzene, reflux, 3 h
View Scheme
参考文献
Strunz, George M.; Ya, Li
Canadian Journal of Chemistry, 1992 , vol. 70, # 5 p. 1317 - 1322
