1.1: thionyl chloride / 3 h / Reflux 2.1: dichloromethane / 0 - 20 °C 3.1: diethylamino-sulfur trifluoride / dichloromethane / 1.25 h / -78 °C 3.2: 4 h / -78 - 20 °C 4.1: selenium(IV) oxide / ethyl acetate / 1 h / 75 °C 5.1: platinum(IV) oxide; hydrogen / 3040.2 Torr 6.1: 20 wt. Pd(OH)2 on activated carbon; hydrogen; trifluoroacetic acid / water / 24 h / 20 °C / 3040.2 Torr View Scheme

1: SOCl2 / 12 h / Ambient temperature 2: diethyl ether / 1.5 h / 0 °C 3: HBr / 0.5 h / 0 °C 4: 98 percent / AgNO3 / acetonitrile / 12 h 5: 88 percent / NaOAc*3H2O, DMSO / 0.42 h / Ambient temperature 6: 62 percent / conc. aq. HCl / ethanol / 4.5 h / 80 °C View Scheme

暂无反应条件数据

mercury(II) fluoride; oxygen in acetonitrile T=25°C; 24 h; Irradiation;

1.1: thionyl chloride / 3 h / Reflux 2.1: dichloromethane / 0 - 20 °C 3.1: diethylamino-sulfur trifluoride / dichloromethane / 1.25 h / -78 °C 3.2: 4 h / -78 - 20 °C 4.1: selenium(IV) oxide / ethyl acetate / 1 h / 75 °C 5.1: platinum(IV) oxide; hydrogen / 3040.2 Torr 6.1: 20 wt. Pd(OH)2 on activated carbon; hydrogen; trifluoroacetic acid / water / 24 h / 20 °C / 3040.2 Torr 7.1: hydrogenchloride; water / 24 h / 90 - 100 °C View Scheme

sodium acetate T=210 - 220°C; Erwaermen des Reaktionsprodukts mit Natriummethylat in Methanol;

sodium hydroxide in dichloromethane T=20°C; 1 h;

T=140°C; 4 h;

1: aqueous sulfuric acid; aqueous sodium nitrite solution / Eintragen des Reaktionsgemisches in wss. Schwefelsaeure 2: sulfuric acid View Scheme

1: aq.-ethanolic solution; hydroxylamine 3: acetic acid; aqueous sulfuric acid 4: sulfuric acid View Scheme