3,5-二甲基吡唑-1-硝酸咪合成路线 （共 18 条）
参考文献
P.Groth, Chemische Krystallographie 5.Teil <Leipzig 1919> S. 577
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Thiele; Dralle
Justus Liebigs Annalen der Chemie, 1898 , vol. 302, p. 282,283
参考文献
Scott et al.
Journal of the American Chemical Society, 1953 , vol. 75, p. 4053
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Bannard et al.
Canadian Journal of Chemistry, 1958 , vol. 36, p. 1541,1547
参考文献
Scott et al.
Journal of the American Chemical Society, 1953 , vol. 75, p. 4053
参考文献
Werbel, Leslie M.; Elslager, Edward F.; Hess, Carolyn; Hutt, Marland P.
Journal of Medicinal Chemistry, 1987 , vol. 30, # 11 p. 1943 - 1948
反应条件
triethylamine in ethanol
pH=9 - 10; 6 h; Heating;
参考文献
Jefford, Charles W.; Rossier, Jean-Claude; Boukouvalas, John; Sledeski, Adam W.; Huang, Ping-Zhong
Journal of Natural Products, 2004 , vol. 67, # 8 p. 1383 - 1386
反应条件
N-ethyl-N,N-diisopropylamine; trifluoroacetic acid in N,N-dimethyl-formamide
参考文献
Merck and Co., Inc.
Patent: US6090805 A1, 2000 ;
US 6090805 A
反应条件
sodium hydroxide in water
120 h; Ambient temperaturepH 10.4;
参考文献
Kamiyama; Satoh; Umino; Katoh; Uemura; Nakamura; Yokose
Journal of Antibiotics, 1995 , vol. 48, # 11 p. 1226 - 1233
参考文献
Borne,R.F. et al.
Journal of Medicinal Chemistry, 1977 , vol. 20, p. 771 - 776
