2-(苯基甲基)吡啶-3-醇合成路线 （共 7 条）
反应条件
1: With trifluoroacetic acid
T=20 - 50°C; 3 h;
2: With potassium carbonate in water
参考文献
Eisai Co., Ltd.
Patent: EP1375496 A1, 2004 ;
Location in patent: Page 38; 30 ;
反应条件
triethylamine in acetonitrile
T=150°C; 1 h; Inert atmosphereMicrowave irradiation;
参考文献
Jouanno, Laurie-Anne; Di Mascio, Vincent; Tognetti, Vincent; Joubert, Laurent; Sabot, Cyrille; Renard, Pierre-Yves
Journal of Organic Chemistry, 2014 , vol. 79, # 3 p. 1303 - 1319
反应条件
ammonia; water
T=175°C;
参考文献
Gruber
Canadian Journal of Chemistry, 1953 , vol. 31, p. 564,566
反应条件
hydrogenchloride
24 h; Heating;
参考文献
Katritzky, Alan R.; Cutler, Alan T.; Dennis, Nicolas; Sabongi, Gebran J.; Rahimi-Rastgoo, Soheila; et al.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1980 , p. 1176 - 1184
反应条件
1: 27 percent / Et3N / CH2Cl2 / 1.) 0 deg C, 15 min, 2.) room temperature, 2 h
2: 50 percent / 50percent HCl / 24 h / Heating
View Scheme
参考文献
Katritzky, Alan R.; Cutler, Alan T.; Dennis, Nicolas; Sabongi, Gebran J.; Rahimi-Rastgoo, Soheila; et al.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1980 , p. 1176 - 1184
反应条件
1: aqueous hydriodic acid
2: water; ammonia / 175 °C
View Scheme
参考文献
Gruber
Canadian Journal of Chemistry, 1953 , vol. 31, p. 564,566
参考文献
Leditschke
Chemische Berichte, 1953 , vol. 86, p. 123,125
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Gruber
Canadian Journal of Chemistry, 1953 , vol. 31, p. 564,566
