4-雄烯-11β-醇-3,17-二酮 合成路线 (共 31 条)
反应条件
Chlorella vulgaris MCCS 013 culture inocula in ethanol T=25°C; 336 h; Microbiological reactionFluorescent illuminationBG-11 liquid medium; stereospecific reaction;
参考文献
Ghasemi, Younes; Rasoul-Amini, Sara; Morowvat, Mohammad Hossein; Ghoshoon, Mohammad Bagher; Raee, Mohammad Javad; Khoubani, Soraya; Negintaji, Narges; Nouri, Fatemeh; Parvizi, Rezvan
Chemistry of Natural Compounds, 2009 , vol. 45, # 6 p. 824 - 828
反应条件
phosphate buffer; D-glucose; tieghemella orchidis; calcium chloride in methanol T=28°C; 24 h; other derivatives of androstene, other microbiological reagents, var reactions; Product distribution;
参考文献
Kolyvanova, T.S.; Bayunova, V.I.; Gabinskaya, K.N.; Korobova, Yu.N.; Grinenko, G.S.
Pharmaceutical Chemistry Journal, 1989 , vol. 23, # 5 p. 441 - 444
Khimiko-Farmatsevticheskii Zhurnal, 1989 , vol. 23, # 5 p. 635 - 637
反应条件
mit Hilfe von Trichomonas gallinae;
参考文献
Sebek; Michaels
Nature (London, United Kingdom), 1957 , vol. 179, p. 210
参考文献
Bernstein et al.
Journal of Organic Chemistry, 1953 , vol. 18, p. 1166,1170,1171
反应条件
1: lithium alanate; diethyl ether 2: aqueous acetic acid View Scheme
参考文献
Bernstein et al.
Journal of Organic Chemistry, 1953 , vol. 18, p. 1166,1170,1171
反应条件
Aspergillus fumigatus ATTC 26934
参考文献
G.D. SEARLE and CO.
Patent: EP1223174 A2, 2002 ;
Location in patent: Example 19A ;
反应条件
sodium periodate 24 h; Ambient temperature;
参考文献
Sato, Seiji; Nakada, Masahisa; Shibasaki, Masakatsu
Tetrahedron Letters, 1996 , vol. 37, # 34 p. 6141 - 6144
→
反应条件
3597-45-3 (8S,9S,10R,11S,13S,14S)-11,17-二羟基-10,13-二甲基-3-氧代-2,6,7,8,9,11,12,14,15,16-十氢-1H-环戊二烯并[a]菲-17-羧酸
反应条件
potassium hydroxide in ethanol 1.66667 h; Ambient temperaturein presence and absence of O2, further reagent: NaOMe; Mechanism;
参考文献
Simons, S. Stoney; Merchlinsky, Michael J.; Johnson, David F.
Steroids, 1981 , vol. 37, # 3 p. 281 - 290
反应条件
silica gel in solid 96 h; Irradiation;
参考文献
Kane; Tsuji
Journal of Pharmaceutical Sciences, 1983 , vol. 72, # 1 p. 30 - 35
反应条件
potassium hydroxide in ethanol Ambient temperature; Product distribution;
参考文献
Simons, S. Stoney; Merchlinsky, Michael J.; Johnson, David F.
Steroids, 1981 , vol. 37, # 3 p. 281 - 290