2-疏基-5,6-二甲基噻吩并[2,3-d]嘧啶-4(3h)-酮合成路线 (共 4 条)
反应条件
sodium hydroxide 48 h; Ambient temperature;
参考文献
Wippich, Petra; Hendreich, Claudia; Guetschow, Michael; Leistner, Siegfried
Synthesis, 1996 , # 6 p. 741 - 747
反应条件
1: 5,6-dimethyl-2-thioxo-1,2,3,4-tetrahydrothieno[2,3-d]pyrimidin-4-one With potassium hydroxide
Metallation; 0.5 h; Heating;
2: methyl iodide in ethanol
Methylation; 5 h; Heating;
参考文献
Abdel-Fattah; Aly; Gad; Zaki; El-Gazzar
Phosphorus, Sulfur and Silicon and Related Elements, 1998 , vol. 141, p. 263 - 281
反应条件
sodium hydroxide in water
参考文献
Hamed, Atef A.; El-Ashry, El-Sayed H.; Zeid, Ibrahim F.; Badr, Hesham F.
Journal of Chemical Research, 2008 , # 6 p. 334 - 339
参考文献
Sauter,F. et al.
Monatshefte fuer Chemie, 1974 , vol. 105, p. 1258 - 1265