反应条件
1: 95 percent / n-BuLi / tetrahydrofuran; hexane / 1 h / -78 - -70 °C 2: 94 percent / NaBH4 / tetrahydrofuran / 18 h / Ambient temperature 3: 1) trifluoroacetic anhydride, DMSO, 2) Et3N / 1) CH2Cl2, -75 to -65 deg C, 1 h, 2a) CH2Cl2, -75 to -65 deg C, 2b) to 0 deg C 4: 76 percent / 18-crown-6, K2CO3 / toluene / 8 h / Ambient temperature 5: 75 percent / NaBH4, cerous chloride / ethanol; tetrahydrofuran / 1 h / -78 - -70 °C 6: 52 percent / Ph3P, DEAD / tetrahydrofuran / a) -10 to -15 deg C, 1 h, b) ice-bath temp., 18 h 7: 74 percent / hydrazine monohydrate / methanol; tetrahydrofuran / 3 h / Ambient temperature 8: 62 percent / Na, NH3 liq. / tetrahydrofuran / 2 h / -70 - -65 °C View Scheme
参考文献
Fukase; Horii
Journal of Organic Chemistry, 1992 , vol. 57, # 13 p. 3651 - 3658
