2,2′-双(溴甲基)-1,1′-联苯合成路线 （共 52 条）
反应条件
1: (i) Ph3P, THF, (ii) PhLi, Et2O, (iii) /BRN= 1209228/ 2: KOtBu / tetrahydrofuran 3: H2 / Pd-C / ethyl acetate View Scheme
参考文献
Staab,H.A. et al.
Chemische Berichte, 1972 , vol. 105, p. 2310 - 2319
反应条件
T=550 - 825°C; P=1 Torr; flow-vacuum pyrolysis; Further byproducts given;
参考文献
Istrati, Daniela; Marton, George; Draghici, Constantin; Grigore, Adriana; Banciu, Mircea D.
Revue Roumaine de Chimie, 2005 , vol. 50, # 7-8 p. 719 - 724
反应条件
1: (i) Ph3P, THF, (ii) PhLi, Et2O, (iii) /BRN= 1209228/ 2: KOtBu / tetrahydrofuran 3: (i) MeLi, THF, Et2O, (ii) /BRN= 1098276/ View Scheme
参考文献
Staab,H.A. et al.
Chemische Berichte, 1972 , vol. 105, p. 2310 - 2319
反应条件
1: AcOH 2: KOH, H2O / ethanol View Scheme
参考文献
Wenner
Journal of Organic Chemistry, 1952 , vol. 17, p. 523,527
反应条件
(i) Ph3P, THF, (ii) PhLi, Et2O, (iii) /BRN= 1209228/; Multistep reaction;
参考文献
Staab,H.A. et al.
Chemische Berichte, 1972 , vol. 105, p. 2310 - 2319
参考文献
Istrati, Daniela; Parvulescu, Luminitza; Popescu, Angela; Mihaiescu, Dan; Andrei, Elena; Badea, Florin
Revue Roumaine de Chimie, 2009 , vol. 54, # 10 p. 847 - 850
反应条件
1: 1.) tBuOCONHNH2, 2.) conc. HCl / 1.) DMF, 1 h, r.t., 2.) 1 h, r.t. 2: 1.) Br2, 2.) Et3N / 1.) benzene, 1 h, 2.) 16 h, r.t. 3: 97 percent / Et3O(1+)*BF4(1-) / CH2Cl2 / 1 h 4: 11.5 percent / NO(+)PF6(-) / acetonitrile / 1 h / Ambient temperature View Scheme
参考文献
Kreher, Richard; Gerhardt, Werner
Liebigs Annalen der Chemie, 1981 , # 2 p. 240 - 247
反应条件
hydrogen bromide in sulfuric acid; water
Heating;
参考文献
Sindelar, Karel; Holubek, Jiri; Ryska, Miroslav; Koruna, Ivan; Protiva, Miroslav
Collection of Czechoslovak Chemical Communications, 1986 , vol. 51, # 12 p. 2848 - 2868
反应条件
in CaCl2; dichloromethane; water
参考文献
Eastman Kodak Company
Patent: US4694109 A1, 1987 ;
反应条件
N-bromosuccinmide; meta-chloroperoxybenzoic acid in tetrachloromethane
Heating;
参考文献
Yamato, Takehiko; Sakaue, Naozumi; Fujita, Koji
Organic Preparations and Procedures International, 1998 , vol. 30, # 3 p. 331 - 337
