2-溴-4'-(三氟甲基)苯乙酮合成路线 （共 25 条）
反应条件
trimethylsilyl bromide; potassium nitrate in dichloromethane T=20°C; 16 h;
参考文献
Prakash, G.K. Sxurya; Ismail, Rehana; Garcia, Jessica; Panja, Chiradeep; Rasul, Golam; Mathew, Thomas; Olah, George A.
Tetrahedron Letters, 2011 , vol. 52, # 11 p. 1217 - 1221
反应条件
water; silver fluoride; trifluoroacetic acid T=40°C; 6 h; Green chemistry;
参考文献
Chen, Zheng-Wang; Ye, Dong-Nai; Ye, Min; Zhou, Zhong-Gao; Li, Shen-Huan; Liu, Liang-Xian
Tetrahedron Letters, 2014 , vol. 55, # 7 p. 1373 - 1375
反应条件
bromine in dichloromethane Heating;
参考文献
Feng, Dong-Zhi; Song, Yan-Li; Jiang, Xiao-Hua; Chen, Li; Long, Ya-Qiu
Organic and Biomolecular Chemistry, 2007 , vol. 5, # 16 p. 2690 - 2697
反应条件
bromine in chloroform T=25 - 28°C; 3.5 - 24 h;
参考文献
CENTRAL GLASS COMPANY, LIMITED
Patent: WO2004/14887 A1, 2004 ;
Location in patent: Page 11; 25-26 ;
反应条件
bromine T=26 - 28°C; 3.5 - 24 h;
参考文献
CENTRAL GLASS COMPANY, LIMITED
Patent: WO2004/14887 A1, 2004 ;
Location in patent: Page 11; 23-24 ;
反应条件
1: sodium azide / methanol; water / 15 h / 0 - 20 °C 2: hydrogenchloride; palladium 10 on activated carbon; hydrogen / methanol; water / 21 h / 20 °C / Cooling with NaCl-ice View Scheme
参考文献
Kuwano, Ryoichi; Kameyama, Nao; Ikeda, Ryuhei
Journal of the American Chemical Society, 2011 , vol. 133, # 19 p. 7312 - 7315
反应条件
1.1: 95 percent / ethanol / 4 h / 45 °C 2.1: 95 percent / lithium diisopropylamide / CH2Cl2 / 0.75 h / -50 °C 3.1: n-butyllithium / tetrahydrofuran / 0.5 h / -74 °C 3.2: SO2 / tetrahydrofuran / -50 - 20 °C 4.1: HF / acetonitrile; H2O / 4 h 5.1: sulfuryl chloride / acetonitrile / 0.5 h / 2 °C View Scheme
参考文献
Ikemoto, Norihiro; Liu, Jinchu; Brands, Karel M.J.; McNamara, James M.; Reider, Paul J.
Tetrahedron, 2003 , vol. 59, # 8 p. 1317 - 1325
反应条件
tetrabutylammonium hydrogen bifluoride in tetrahydrofuran Heating;
参考文献
Fuglseth, Erik; Thvedt, Thor Hakon Krane; Moll, Maria Forde; Hoff, Bard Helge
Tetrahedron, 2008 , vol. 64, # 30-31 p. 7318 - 7323
反应条件
ammonium chloride; zinc in ethanol T=80°C; 0.00833333 h; microwave irradiation;
参考文献
Li, Jian; Ye, Deju; Liu, Hong; Luo, Xiaoming; Jiang, Hualiang
Synthetic Communications, 2008 , vol. 38, # 4 p. 567 - 575
反应条件
sodium hydroxide in ethanol; water T=20°C; 0.583333 h;
参考文献
Ge, Min; Cline, Eric; Yang, Lihu; Mills, Sander G.
Patent: US2009/253673 A1, 2009 ;
Location in patent: Page/Page column 26 ;
US 20090253673 A1
