反应条件
1: C10H8BrClN2; C10H8BrClN2 With isopropylmagnesium chloride in tetrahydrofuran T=0 - 10°C; 1.5 h; 2: ethyl-α,α,α-trifluoroacetate in tetrahydrofuran T=-20 - 0°C; 1.25 h;
参考文献
Bednarz, Mark S.; Burgoon, JR., Hugh Alfred; Iimura, Shinya; Kanamarlapudi, Ramanaiah C.; Song, Qiuling; Wu, Wenxue; Yan, Jie; Zhang, Haiming
Patent: US2009/62540 A1, 2009 ;
Location in patent: Page/Page column 7 ;
