2-(3-溴苯基)-吡咯烷合成路线 （共 3 条）
反应条件
1: With sodium tetrahydroborate in ethanol T=20°C; 2: With hydrogenchloride; water in ethanol T=0°C; pH=1; 0.75 h; 3: With sodium hydroxide; water in ethanol
参考文献
Apodaca, Richard; Barbier, Ann J.; Carruthers, Nicholas I.; Gomez, Leslie A.; Keith, John M.; Lovenberg, Timothy W.; Wolin, Ronald L.
Patent: US2006/293316 A1, 2006 ;
Location in patent: Page/Page column 60 ;
US 20060293316 A1
反应条件
1.1: Mg / tetrahydrofuran / 1 h / Heating 1.2: tetrahydrofuran / 18 h / 20 °C 1.3: 63 percent / HCl / ethanol; tetrahydrofuran / 3 h / 20 °C 2.1: NaBH4; acetic acid / methanol / -45 °C View Scheme
参考文献
Rogers, Claude J.; Dickerson, Tobin J.; Brogan, Andrew P.; Janda, Kim D.
Journal of Organic Chemistry, 2005 , vol. 70, # 9 p. 3705 - 3708
反应条件
N-ethyl-N,N-diisopropylamine in tetrahydrofuran
T=20°C; 5 h;
参考文献
Apodaca, Richard; Barbier, Ann J.; Carruthers, Nicholas I.; Gomez, Leslie A.; Keith, John M.; Lovenberg, Timothy W.; Wolin, Ronald L.
Patent: US2006/293316 A1, 2006 ;
Location in patent: Page/Page column 60 ;
US 20060293316 A1
