4,6-二甲基-1H-吲哚-2-羧酸合成路线 （共 3 条）
反应条件
1: With lithium hydroxide in ethanol Heating / reflux; 2: With hydrogenchloride in ethanol; water pH=3;
参考文献
US2009/137635 A1, ;
Page/Page column 7 ;
反应条件
1: p-toluenesulfonic acid monohydrate / benzene / |Reflux; |Dean-Stark 2: lithium hydroxide hydrate; ethanol / |Reflux View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 56, # 10 p. 4093 - 4103
反应条件
copper in quinoline T=230°C; 3 h;
参考文献
Onajole, Oluseye K.; Pieroni, Marco; Tipparaju, Suresh K.; Lun, Shichun; Stec, Jozef; Chen, Gang; Gunosewoyo, Hendra; Guo, Haidan; Ammerman, Nicole C.; Bishai, William R.; Kozikowski, Alan P.
Journal of Medicinal Chemistry, 2013 , vol. 56, # 10 p. 4093 - 4103
