6-硝基-2-苯基苯并噻唑合成路线 （共 12 条）
反应条件
nitric acid
T=5°C; 1.16667 h;
参考文献
ROTTAPHARM SPA
Patent: US2005/197331 A1, 2005 ;
Location in patent: Page/Page column 14 ;
反应条件
copper(l) iodide; dichloro(cycloocta-1,5-diene)palladium(II); tetrabutylammomium bromide in 1-methyl-pyrrolidin-2-one; dimethyl sulfoxide
T=120°C; 2 h; Inert atmosphere;
参考文献
Inamoto, Kiyofumi; Hasegawa, Chisa; Hiroya, Kou; Doi, Takayuki
Organic Letters, 2008 , vol. 10, # 22 p. 5147 - 5150
反应条件
1,4-diaza-bicyclo[2.2.2]octane; 1,10-phenanthroline; copper (II) acetate monohydrate; sulfur in dimethyl sulfoxide
T=100°C;
参考文献
Wang, Rui; Ding, Yong-Liang; Liu, Hong; Peng, Shu; Ren, Jie; Li, Lei
Tetrahedron Letters, 2014 , vol. 55, # 4 p. 945 - 949
反应条件
nitric acid in concentrated H2 SO4
参考文献
Hoffmann-La Roche Inc.
Patent: US6153634 A1, 2000 ;
US 6153634 A
反应条件
iron sulphate heptahydrate; oxygen in diethylene glycol dimethyl ether; water
T=150°C; 20 h; Sealed tube;
参考文献
Liu, Saiwen; Chen, Ru; Guo, Xiangyu; Yang, Huiqiong; Deng, Guojun; Li, Chao-Jun
Green Chemistry, 2012 , vol. 14, # 6 p. 1577 - 1580
反应条件
tri(n-propyl)amine; copper(l) iodide; 1,10-phenanthroline in 1,4-dioxane
T=20 - 100°C; Wittig Olefination; 32.0833 h; Inert atmosphere;
参考文献
Yu, Hui; Zhang, Meishu; Li, Yuzhe
Journal of Organic Chemistry, 2013 , vol. 78, # 17 p. 8898 - 8903
反应条件
oxygen; cesium fluoride; palladium dichloride in dimethyl sulfoxide
T=100°C; 12 h;
参考文献
Inamoto, Kiyofumi; Hasegawa, Chisa; Kawasaki, Junpei; Hiroya, Kou; Doi, Takayuki
Advanced Synthesis and Catalysis, 2010 , vol. 352, # 14-15 p. 2643 - 2655
反应条件
1: sulfur
2: HNO3+H2SO4 / 90 - 95 °C
View Scheme
参考文献
Naegeli
Bulletin de la Societe Chimique de France, 1894 , vol. <3> 11, p. 894
反应条件
1: sulfur
2: durch Nitrierung
View Scheme
参考文献
Bogert; Abrahamson
Journal of the American Chemical Society, 1922 , vol. 44, p. 834
反应条件
1: toluene; phosphorus pentasulfide
2: potassium iron (III)-cyanide; diluted NaOH-solution
View Scheme
参考文献
Fries
Justus Liebigs Annalen der Chemie, 1927 , vol. 454, p. 306
