(9ci)-1-甲基-2-(三氟甲基)-1H-苯并咪唑合成路线 （共 8 条）
反应条件
1: 95 percent / 10 h / 80 °C 2: 1.) 0.1 M aq. NaOH / 1.) RT, 2.) water, reflux, 30 min View Scheme
参考文献
Glowczyk, Joanna; Serafin, Barbara
Polish Journal of Chemistry, 1984 , vol. 58, # 1-3 p. 149 - 156
参考文献
Rene, Olivier; Souverneva, Alexandra; Magnuson, Steven R.; Fauber, Benjamin P.
Tetrahedron Letters, 2013 , vol. 54, # 3 p. 201 - 204
反应条件
copper in N,N-dimethyl-formamide
T=60°C; 11 h;
参考文献
Zhang, Cheng-Pan; Wang, Zong-Ling; Chen, Qing-Yun; Zhang, Chun-Tao; Gu, Yu-Cheng; Xiao, Ji-Chang
Angewandte Chemie - International Edition, 2011 , vol. 50, # 8 p. 1896 - 1900
反应条件
in N,N-dimethyl-formamide
T=80°C; 8 h; Sealed tubeInert atmosphere;
参考文献
Mormino, Michael G.; Fier, Patrick S.; Hartwig, John F.
Organic Letters, 2014 , vol. 16, # 6 p. 1744 - 1747
反应条件
1,10-phenanthroline; di-tert-butyl peroxide; copper diacetate; sodium acetate; sodium t-butanolate in 1,2-dichloro-ethane
T=80°C; 6.03333 h; Inert atmosphereMolecular sieve;
参考文献
Chu, Lingling; Qing, Feng-Ling
Journal of the American Chemical Society, 2012 , vol. 134, # 2 p. 1298 - 1304
反应条件
1: H2 / Raney Ni / tetrahydrofuran
2: H2O / Heating
View Scheme
参考文献
Navarrete-Vazquez, Gabriel; Cedillo, Roberto; Hernandez-Campos, Alicia; Yepez, Lilian; Hernandez-Luis, Francisco; Valdez, Juan; Morales, Raul; Cortes, Rafael; Hernandez, Manuel; Castillo, Rafael
Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 2 p. 187 - 190
反应条件
1: H2O / Heating
View Scheme
参考文献
Navarrete-Vazquez, Gabriel; Cedillo, Roberto; Hernandez-Campos, Alicia; Yepez, Lilian; Hernandez-Luis, Francisco; Valdez, Juan; Morales, Raul; Cortes, Rafael; Hernandez, Manuel; Castillo, Rafael
Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 2 p. 187 - 190
参考文献
Navarrete-Vazquez, Gabriel; Cedillo, Roberto; Hernandez-Campos, Alicia; Yepez, Lilian; Hernandez-Luis, Francisco; Valdez, Juan; Morales, Raul; Cortes, Rafael; Hernandez, Manuel; Castillo, Rafael
Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 2 p. 187 - 190
