3,4,5-三甲氧基苄氯合成路线 （共 34 条）
反应条件
1: NaI 2: aq. HCl View Scheme
参考文献
Zheng, Cheng; Guo, Yibing; Meng, Ying; Dou, Sufeng; Shao, Jian; Yang, Yumin
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2013 , vol. 52, # 5 p. 654 - 664
反应条件
magnesium; ethylene dibromide 1.) THF, RT, 1h; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Yamada; Itoh; Ikezawa; Kiyomoto; Iwakuma
Chemical and Pharmaceutical Bulletin, 1981 , vol. 29, # 7 p. 1848 - 1853
反应条件
carbon dioxide; magnesium; ethylene dibromide 1.) THF, r.t., 1 h, 2.) r.t.; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Yamada; Itoh; Ikezawa; Kiyomoto; Iwakuma
Chemical and Pharmaceutical Bulletin, 1981 , vol. 29, # 7 p. 1848 - 1853
反应条件
1: Na / ethanol / Heating 2: aq. HCl View Scheme
参考文献
Schmidt; Rosenkranz
Justus Liebigs Annalen der Chemie, 1976 , vol. no.1, p. 129 - 139
反应条件
[C12mim][FeCl4]; periodic acid T=30°C; 1.5 h;
参考文献
Hu, Yu Lin; Liu, Qi Fa; Lu, Ting Ting; Lu, Ming
Catalysis Communications, 2010 , vol. 11, # 10 p. 923 - 927
反应条件
1: NaI 2: aq. HCl 3: H2SO4 View Scheme
参考文献
Cason,J.; Lynch,D.M.
Journal of Organic Chemistry, 1966 , vol. 31, p. 1883 - 1887
反应条件
lithium aluminium tetrahydride in tetrahydrofuran Heating;
参考文献
Musso,H. et al.
Chemische Berichte, 1962 , vol. 95, p. 2837 - 2843
反应条件
1: potassium carbonate / dimethyl sulfoxide / 6 h / 50 °C 2: sodium chloride / dimethyl sulfoxide / 5 h / |Reflux View Scheme
参考文献
Zheng, Cheng; Guo, Yibing; Meng, Ying; Dou, Sufeng; Shao, Jian; Yang, Yumin
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2013 , vol. 52, # 5 p. 654 - 664
反应条件
1.1: 80 percent / toluene 2.1: butyllithium / hexane; tetrahydrofuran / 15 - 20 °C 2.2: hexane; tetrahydrofuran / 1 h / 20 °C 3.1: tetrabutylammonium fluoride / tetrahydrofuran / 0.25 h / 20 °C View Scheme
参考文献
Carbohydrate Research, , vol. 301, # 3-4 p. 95 - 109
反应条件
1: 5-(chloromethyl)-1,2,3-trimethoxybenzene With tributylphosphine in tetrahydrofuran T=0°C; Wittig reaction; 0.0833333 h; 2: 4-methoxy-benzaldehyde With tetrabutyl ammonium fluoride in tetrahydrofuran T=20°C; Wittig reaction; 16 h; optical yield given as percent dediastereoselective reaction;
参考文献
Fumagalli, Tiziano; Sello, Guido; Orsini, Fulvia
Synthetic Communications, 2009 , vol. 39, # 12 p. 2178 - 2195
