3,4,5-三甲氧基苄醇合成路线 （共 102 条）
反应条件
1: (4-methoxybenzyl)triphenylphosphonium chloride With n-butyllithium in tetrahydrofuran; hexane T=0°C; Wittig type reaction; 2: 3,4,5-trimethoxy-benzyl alcohol With 4,4'-di-tert-butylbiphenyl; lithium; nickel dichloride in tetrahydrofuran; hexane Wittig type reaction; 12 h; Inert atmosphereReflux;
参考文献
Alonso, Francisco; Riente, Paola; Yus, Miguel
European Journal of Organic Chemistry, 2009 , # 34 p. 6034 - 6042
反应条件
1: PBr3 / CH2Cl2 / 0.75 h / -5 °C 2: 73 percent / 2.17 h / 140 - 180 °C 3: 76 percent / NaH; 15-crown-5 / tetrahydrofuran View Scheme
参考文献
Ao, Junli; Chen, Yuanmou; Xu, Xiaoling; Zhang, Xu; Yu, Yue; Yu, Peng; Hua, Erbing
Asian Journal of Chemistry, 2014 , vol. 26, # 7 p. 2092 - 2098
反应条件
1: 85 percent / pyridinium chlorochromate / CH2Cl2 / 20 °C 2: 92 percent / NaH; PhSH; HMPT / toluene / Heating View Scheme
参考文献
Zou, Hong Bin; Dong, Sheng Yi; Zhou, Chang Xin; Hu, Li Hong; Wu, Yi Hang; Li, Hai Bo; Gong, Jing Xu; Sun, Lian Li; Wu, Xiu Mei; Bai, Hua; Fan, Bo Tao; Hao, Xiao Jiang; Stoeckigt, Joachim; Zhao, Yu
Bioorganic and Medicinal Chemistry, 2006 , vol. 14, # 6 p. 2060 - 2071
反应条件
1: SOCl2 / dioxane / 20 °C 2: acetonitrile / 20 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 11, # 16 p. 2205 - 2208
反应条件
1: 85 percent / pyridinium chlorochromate / CH2Cl2 / 20 °C 2: 30 percent / AlCl3 / CH2Cl2 / 12 h / 20 °C View Scheme
参考文献
Zou, Hong Bin; Dong, Sheng Yi; Zhou, Chang Xin; Hu, Li Hong; Wu, Yi Hang; Li, Hai Bo; Gong, Jing Xu; Sun, Lian Li; Wu, Xiu Mei; Bai, Hua; Fan, Bo Tao; Hao, Xiao Jiang; Stoeckigt, Joachim; Zhao, Yu
Bioorganic and Medicinal Chemistry, 2006 , vol. 14, # 6 p. 2060 - 2071
反应条件
1: 80 percent / N-bromosuccinimide / CHCl3 / 3 h / Heating 2: 85 percent / MnO2 / benzene View Scheme
参考文献
Ziegler, Frederick E.; Chliwner, Irene; Fowler, Kerry W.; Kanfer, Sheldon J.; Kuo, Stephen J.; Sinha, Nanda D.
Journal of the American Chemical Society, 1980 , vol. 102, # 2 p. 790 - 798
反应条件
1: 85 percent / pyridinium chlorochromate / CH2Cl2 / 20 °C 2: methanol / 24 h / 20 °C View Scheme
参考文献
Zou, Hong Bin; Dong, Sheng Yi; Zhou, Chang Xin; Hu, Li Hong; Wu, Yi Hang; Li, Hai Bo; Gong, Jing Xu; Sun, Lian Li; Wu, Xiu Mei; Bai, Hua; Fan, Bo Tao; Hao, Xiao Jiang; Stoeckigt, Joachim; Zhao, Yu
Bioorganic and Medicinal Chemistry, 2006 , vol. 14, # 6 p. 2060 - 2071
反应条件
CuO*Fe3O4; sodium hydroxide in toluene T=100°C; 96 h; Inert atmosphere;
参考文献
Perez, Juana M.; Cano, Rafael; Yus, Miguel; Ramon, Diego J.
European Journal of Organic Chemistry, 2012 , # 24 p. 4548 - 4554
反应条件
1.1: sodium hydride / tetrahydrofuran / 0.5 h / 0 - 20 °C / |Inert atmosphere 1.2: 16 h / |Inert atmosphere; |Reflux 2.1: N,N,N',N'-tetramethyl-7,8-dihydro-6H-dipyrido[1,2-a;2',1'-c][1,4] diazepine-2,12-diamine / N,N-dimethyl-formamide / 72 h / |Inert atmosphere; |Glovebox; |UV-irradiation View Scheme
参考文献
Doni, Eswararao; O'Sullivan, Steven; Murphy, John A.
Angewandte Chemie - International Edition, 2013 , vol. 52, # 8 p. 2239 - 2242
Angew. Chem., 2013 , vol. 125, # 8 p. 2295 - 2298,4
反应条件
dihydrogen peroxide in water; toluene T=20 - 85°C; 4 h;
参考文献
Hu, Yu Lin; Ma, Xiao Yun; Ge, Qiang; Lu, Ming
Acta Chimica Slovenica, 2010 , vol. 57, # 4 p. 927 - 930
