1: 2-bromo-5-methyl-1,4-dimethoxybenzene With n-butyllithium in tetrahydrofuran; hexane T=-78°C; 0.333333 h; Inert atmosphere; 2: oxirane in tetrahydrofuran; hexane T=-78°C; 0.333333 h; Inert atmosphere; 3: With boron trifluoride diethyl etherate in tetrahydrofuran; hexane Inert atmosphere;

diethyl ether anschliessendes Behandeln mit wss. H2SO4;

1: acetic acid; aqueous HBr 2: potassium carbonate; acetone View Scheme