3-氯-2,4-二氟硝基苯合成路线 （共 5 条）
反应条件
potassium fluoride; dimethyl sulfoxide T=180°C;
参考文献
Finger; Kruse
Journal of the American Chemical Society, 1956 , vol. 78, p. 6034,6037
参考文献
Rhone-Poulenc Chimie
Patent: US5856577 A1, 1999 ;
反应条件
1: 90 percent / 12 N aq. HCl; SnCl2 / diethyl ether / 0.5 h / 40 °C 2: 74 percent / NBS / dimethylformamide / 1 h / -2 °C View Scheme
参考文献
Tabart, Michel; Picaut, Guy; Lavergne, Marc; Wentzler, Sylvie; Malleron, Jean-Luc; Dutka-Malen, Sylvie; Berthaud, Nadine
Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 7 p. 1329 - 1331
反应条件
hydrogenchloride; tin(ll) chloride in diethyl ether T=40°C; 0.5 h;
参考文献
Tabart, Michel; Picaut, Guy; Lavergne, Marc; Wentzler, Sylvie; Malleron, Jean-Luc; Dutka-Malen, Sylvie; Berthaud, Nadine
Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 7 p. 1329 - 1331
反应条件
in hydrogenchloride; water
参考文献
Desconclois, Jean-Francois; Genevois-Borella, Arielle; Girard, Philippe; Kryvenko, Michel; Lavergne, Marc Pierre; Malleron, Jean-Luc; Picaut, Guy; Tabart, Michel; Wentzler, Sylvie
Patent: US2002/137741 A1, 2002 ;
