2-苯基苯并二氢吡喃-7-醇合成路线 （共 7 条）
反应条件
hydrogen; palladium 10 on activated carbon in ethyl acetate
T=20°C; P=760.051 Torr; 45 h;
参考文献
NOVARTIS AG; IRM LLC, a Delaware Limited Liability Company; CHEN, Bei; FAIRHURST, Robin, Alec; FLOERSHEIMER, Andreas; FURET, Pascal; JIANG, Songchun; LU, Wenshuo; MARSILJE, Thomas, H.; VAUPEL, Andrea
Patent: WO2011/64211 A1, 2011 ;
Location in patent: Page/Page column 55 ;
WO 2011/064211 A1
反应条件
1: With triethylsilane in dichloromethane
0.0833333 h;
2: With trifluoroacetic acid in dichloromethane
T=20°C; 0.5 h;
参考文献
NOVARTIS AG; IRM LLC, a Delaware Limited Liability Company; CHEN, Bei; FAIRHURST, Robin, Alec; FLOERSHEIMER, Andreas; FURET, Pascal; JIANG, Songchun; LU, Wenshuo; MARSILJE, Thomas, H.; VAUPEL, Andrea
Patent: WO2011/64211 A1, 2011 ;
Location in patent: Page/Page column 83 ;
WO 2011/064211 A1
反应条件
hydrogenchloride; sodium cyanoborohydride in methanol
参考文献
Elliger, Carl A.
Synthetic Communications, 1985 , vol. 15, # 14 p. 1315 - 1324
反应条件
phosphoric acid in benzene
T=75 - 80°C; 12 h;
参考文献
Ahluwalia, V. K.; Arora, K. K.; Mukherjee, Keya
Synthesis, 1984 , # 4 p. 346 - 348
反应条件
hydrogen; platinum(IV) oxide in acetic acid
参考文献
Coxon, David T.; O'Neill, Timothy M.; Mansfield, John W.; Porter, Alexander E. A.
Phytochemistry (Elsevier), 1980 , vol. 19, p. 889 - 891
反应条件
1: 2.05 g / HCl / ethyl acetate / 72 h / 1 °C
2: 363 mg / H2 / PtO2 / acetic acid
View Scheme
参考文献
Coxon, David T.; O'Neill, Timothy M.; Mansfield, John W.; Porter, Alexander E. A.
Phytochemistry (Elsevier), 1980 , vol. 19, p. 889 - 891
反应条件
1: 2.05 g / HCl / ethyl acetate / 72 h / 1 °C
2: 363 mg / H2 / PtO2 / acetic acid
View Scheme
参考文献
Coxon, David T.; O'Neill, Timothy M.; Mansfield, John W.; Porter, Alexander E. A.
Phytochemistry (Elsevier), 1980 , vol. 19, p. 889 - 891
