3-溴-4-甲氧基苯甲醇合成路线 （共 14 条）
反应条件
diisobutylaluminium hydride in tetrahydrofuran; hexane T=-78 - 0°C; 1 h; Inert atmosphere;
参考文献
Ogura, Tetsuhiro; Usuki, Toyonobu
Tetrahedron, 2013 , vol. 69, # 13 p. 2807 - 2815
反应条件
sodium tetrahydroborate; ethanol in water T=0 - 20°C;
参考文献
Odlo, Kristin; Fournier-Dit-Chabert, Jeremie; Ducki, Sylvie; Gani, Osman A.B.S.M.; Sylte, Ingebrigt; Hansen, Trond Vidar
Bioorganic and Medicinal Chemistry, 2010 , vol. 18, # 18 p. 6874 - 6885
反应条件
copper(ll) bromide in methanol Heating;
参考文献
Thompson, Alicia L. S.; Kabalka, George W.; Akula, Murthy R.; Huffman, John W.
Synthesis, 2005 , # 4 art. no. M05304SS, p. 547 - 550
反应条件
1: 91 percent / pyridine / CH2Cl2 / 0.25 h / 0 °C 2: 67 percent / Et3N / PdCl2(dppf) / dioxane / Heating 3: 59 percent / aq. CuBr2 / methanol / Heating View Scheme
参考文献
Thompson, Alicia L. S.; Kabalka, George W.; Akula, Murthy R.; Huffman, John W.
Synthesis, 2005 , # 4 art. no. M05304SS, p. 547 - 550
反应条件
1: 67 percent / Et3N / PdCl2(dppf) / dioxane / Heating 2: 59 percent / aq. CuBr2 / methanol / Heating View Scheme
参考文献
Thompson, Alicia L. S.; Kabalka, George W.; Akula, Murthy R.; Huffman, John W.
Synthesis, 2005 , # 4 art. no. M05304SS, p. 547 - 550
反应条件
bromine in dichloromethane; water T=20°C; Oxidation; bromination; 5 h; Product distribution; Further Variations:Solvents;
参考文献
Bravo, Anna; Fontana, Francesca; Dordi, Barbara; Minisci, Francesco
Journal of Organic Chemistry, 2000 , vol. 65, # 12 p. 3880 - 3881
反应条件
1: CH3BF3(1-)*H(1+)*C4H10O; N-bromosuccinmide / acetonitrile / 23 h / -10 - 20 °C / |Inert atmosphere 2: diisobutylaluminium hydride / tetrahydrofuran; hexane / 1 h / -78 - 0 °C / |Inert atmosphere View Scheme
参考文献
Ogura, Tetsuhiro; Usuki, Toyonobu
Tetrahedron, 2013 , vol. 69, # 13 p. 2807 - 2815
反应条件
1: potassium carbonate / acetone / 4 h / |Inert atmosphere; |Reflux 2: CH3BF3(1-)*H(1+)*C4H10O; N-bromosuccinmide / acetonitrile / 23 h / -10 - 20 °C / |Inert atmosphere 3: diisobutylaluminium hydride / tetrahydrofuran; hexane / 1 h / -78 - 0 °C / |Inert atmosphere View Scheme
参考文献
Ogura, Tetsuhiro; Usuki, Toyonobu
Tetrahedron, 2013 , vol. 69, # 13 p. 2807 - 2815
反应条件
1: Br2, aq. AcOH, I2 2: HCHO, aq. NaOH View Scheme
参考文献
Gibson,M.S. et al.
Journal of the Chemical Society [Section] C: Organic, 1970 , p. 2234 - 2238
反应条件
1: With oxalyl dichloride; dimethyl sulfate in dichloromethane T=-78°C; Swern Oxidation; 1 h; Inert atmosphere; 2: With triethylamine in dichloromethane T=-78 - 20°C; Swern Oxidation; 2 h; Inert atmosphere;
参考文献
Ogura, Tetsuhiro; Usuki, Toyonobu
Tetrahedron, 2013 , vol. 69, # 13 p. 2807 - 2815
