5-甲基-2-硝基苯甲醚合成路线 （共 55 条）
反应条件
tetra(n-butyl)ammonium hydrogensulfate; potassium hydroxide in water; toluene T=20°C;
参考文献
Sridharan, Vellaisamy; Antonia Martin; Carlos Menendez
European Journal of Organic Chemistry, 2009 , # 27 p. 4614 - 4621
反应条件
sodium hydroxide in water T=80°C;
参考文献
Ismail, Ibrahim A.; Sharp, Dale E.; Chedekel, Miles R.
Journal of Organic Chemistry, 1980 , vol. 45, # 11 p. 2243 - 2246
参考文献
AMBRX, INC.
Patent: WO2007/70659 A2, 2007 ;
Location in patent: Page/Page column 172; 12/40 ;
反应条件
nitric acid; hydrazine T=25°C; Rate constant;
参考文献
Sankararaman,S.; Haney,W.A.; Kochi,J.K.
Journal of the American Chemical Society, 1987 , vol. 109, p. 7824
反应条件
4-Hydroxy-2-methoxy-6-methylbenzoesaeure-methylester; potassium carbonate; copper(II) oxide T=140°C; 16 h;
参考文献
Carvalho, Christopher F.; Sargent, Melvyn V.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1984 , # 7 p. 1613 - 1620
反应条件
in dichloromethane T=25°C; 8 h; Irradiation;
参考文献
Sankararaman,S.; Haney,W.A.; Kochi,J.K.
Journal of the American Chemical Society, 1987 , vol. 109, p. 7824
反应条件
1: 83 percent / aluminium chloride / benzene / 0.5 h / Heating 2: 18 percent / nitric acid, acetic acid / 4 h / 15 - 16 °C / further nitration agents 3: potassium carbonate / dimethylformamide / 14 h / Ambient temperature 4: 17 percent / potassium carbonate, copper(II) oxide / 16 h / 140 °C View Scheme
参考文献
Carvalho, Christopher F.; Sargent, Melvyn V.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1984 , # 7 p. 1613 - 1620
反应条件
1: 18 percent / nitric acid, acetic acid / 4 h / 15 - 16 °C / further nitration agents 2: potassium carbonate / dimethylformamide / 14 h / Ambient temperature 3: 17 percent / potassium carbonate, copper(II) oxide / 16 h / 140 °C View Scheme
参考文献
Carvalho, Christopher F.; Sargent, Melvyn V.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1984 , # 7 p. 1613 - 1620
反应条件
1: 77 percent / bromine, aluminium powder 2: 83 percent / aluminium chloride / benzene / 0.5 h / Heating 3: 18 percent / nitric acid, acetic acid / 4 h / 15 - 16 °C / further nitration agents 4: potassium carbonate / dimethylformamide / 14 h / Ambient temperature 5: 17 percent / potassium carbonate, copper(II) oxide / 16 h / 140 °C View Scheme
参考文献
Chakraborty, Suchandra; Chattopadhyay, Gautam; Saha, Chandan
Journal of Heterocyclic Chemistry, 2013 , vol. 50, # 1 p. 91 - 98
反应条件
potassium carbonate; copper(II) oxide T=140°C; 16 h;
参考文献
Carvalho, Christopher F.; Sargent, Melvyn V.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1984 , # 7 p. 1613 - 1620
