4-(2-(二乙基氨基)乙氧基)-苯胺合成路线 （共 16 条）
反应条件
1: potassium carbonate / acetonitrile / 80 °C
2: palladium 10 on activated carbon; hydrogen / methanol
View Scheme
参考文献
Song, Hyeseung; Lee, Yun Suk; Roh, Eun Joo; Seo, Jae Hong; Oh, Kwang-Seok; Lee, Byung Ho; Han, Hogyu; Shin, Kye Jung
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 17 p. 5668 - 5674
反应条件
1: sodium hydroxide / N,N-dimethyl-formamide / 3 h / 20 °C
2: hydrogenchloride / 1,4-dioxane / 12 h / 20 °C / |Cooling with ice
View Scheme
参考文献
Mooring, Suazette Reid; Liu, Jin; Liang, Zhongxing; Ahn, Jeffrey; Hong, Samuel; Yoon, Younghyoun; Snyder, James P.; Shim, Hyunsuk
ChemMedChem, 2013 , vol. 8, # 4 p. 622 - 632
反应条件
1: potassium carbonate; water; xylene
2: palladium/charcoal / Hydrogenation
View Scheme
参考文献
Kaye et al.
Journal of Organic Chemistry, 1951 , vol. 16, p. 1421,1424
反应条件
anschliessende Hydrolyse;
参考文献
I.G.Farbenind.
Patent: DE582390 , 1928 ;
Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 19, p. 1541
反应条件
in DMF (N,N-dimethyl-formamide)
T=-15 - 20°C; 1 h;
参考文献
Chu, Xin-Jie; Ding, Qingjie; Jiang, Nan; Kim, Kyungjin; Lovey, Allen John; McComas, Warren William; Mullin JR., John Guilfoyle; Tilley, Jefferson Wright
Patent: US2004/6058 A1, 2004 ;
Location in patent: Page/Page column 90 ;
US 20040006058 A1
反应条件
1: aqueous NH3 / beim Erwaermen des Reaktionsgemisches mit wss. Pb(NO3)2
3: bromine; CHCl3
View Scheme
参考文献
Utsumi et al.
Yakugaku Zasshi, 1954 , vol. 74, p. 238,240
Chem.Abstr., 1955 , p. 3163
