2-(苄氧基)-5-氯苯甲醛合成路线 （共 5 条）
反应条件
1: sodium tetrahydroborate / methanol; water / 2 h / 20 °C 2: phosphorus tribromide / toluene / 12 h / 20 °C View Scheme
参考文献
Aitken, R. Alan; Bouquet, Jaufret; Frank, Julia; Gidlow, Anna L. G.; Powder, Yomica L.; Ramsewak, Russel S.; Reynolds, William F.
RSC Advances, 2013 , vol. 3, # 20 p. 7230 - 7232
反应条件
potassium carbonate in N,N-dimethyl-formamide
T=60°C;
参考文献
GLAXO GROUP LIMITED
Patent: WO2005/54191 A1, 2005 ;
Location in patent: Page/Page column 26 ;
反应条件
potassium carbonate; potassium iodide in tetrahydrofuran
6 h; Heating;
参考文献
Lin, Chin-Fen; Yang, Jai-Sing; Chang, Chiung-Yun; Kuo, Sheng-Chu; Lee, Miau-Rong; Huang, Li-Jiau
Bioorganic and Medicinal Chemistry, 2005 , vol. 13, # 5 p. 1537 - 1544
反应条件
1: chlorine; acetic acid / 1.5 h / 20 °C
2: potassium hydroxide / ethanol / 2 h / |Reflux
View Scheme
参考文献
Aitken, R. Alan; Bouquet, Jaufret; Frank, Julia; Gidlow, Anna L. G.; Powder, Yomica L.; Ramsewak, Russel S.; Reynolds, William F.
RSC Advances, 2013 , vol. 3, # 20 p. 7230 - 7232
参考文献
Baker; Gibson
Journal of medicinal chemistry, 1972 , vol. 15, # 6 p. 639 - 642
